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Showing 1–24 of 2,059 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: weight loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

NCT03146156
View directory record Official record
Conditions
Obesity, Lifestyle-related Condition, Macrosomia, Fetal
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
4
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Koa Family Study--A Community-Based Intervention to Improve Health and Well-Being

NCT04662593
View directory record Official record
Conditions
Obesity, Overweight, Diet, Healthy, Social Interaction, Weight Loss
Interventions
Whole Health Program
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 3 Interventional

Weight Loss and Exercise in Physically Limited Obese Elderly Subjects

NCT00146133
View directory record Official record
Conditions
Obesity, Frailty, Elderly
Interventions
diet, exercise
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2006 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Safety and Effectiveness of Low and High Carbohydrate Diets

NCT00079547
View directory record Official record
Conditions
Obesity
Interventions
Low-calorie diet, low-carbohydrate diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Sep 5, 2026, 7:37 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Study of Lung Cancer Screening in People With Unexplained Weight Loss

NCT06717334
View directory record Official record
Conditions
Lung Cancer Screening
Interventions
Low Dose CT imaging, blood draws, screening questionnaire
Diagnostic Test · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 5, 2026, 7:37 PM EDT
Terminated Phase 3 Interventional Results available

Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension

NCT00637806
View directory record Official record
Conditions
Anorexia, Cachexia, Weight Loss
Interventions
Megestrol acetate concentrated suspension 110 mg/mL, Megestrol acetate concentrated suspension 60 mg/mL, Placebo
Drug
Lead sponsor
Par Pharmaceutical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
4
States / cities
Anaheim, California • Flat Rock, North Carolina • High Point, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The WEIGH Study: Weighing to Improve and Gain Health

NCT01369004
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Daily Self-weighing + weekly feedback+ weekly lessons
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Sleep Plus Eating Routines for Weight Loss

NCT01717352
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Weight Loss Education, Sleep and Eating Routine
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 3, 2017 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Low Starch Dietary Education Program vs. Traditional Treatment for PCOS

NCT03916263
View directory record Official record
Conditions
PCOS, Diet Modification, Metabolism, Nutrition Disorders
Interventions
Metformin, One-On-One Dietary Instruction, Video Dietary Instruction
Drug · Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional

Avanzando Juntas: Adapting an Evidence Based Weight Loss Program for Hispanic Breast Cancer Survivors

NCT04321135
View directory record Official record
Conditions
Breast Cancer, Gynecologic Cancer
Interventions
Guided Lifestyle Program Intervention, Self-Guided Lifestyle Program (Control Arm)
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients

NCT02835326
View directory record Official record
Conditions
Osteoarthritis
Interventions
Exercise and Dietary Weight Loss, Walk with Ease
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Probiotics to Aid in Weight Loss

NCT01445704
View directory record Official record
Conditions
Weight Loss
Interventions
Probiotics, Placebo
Dietary Supplement
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional

mHealth Messages to Sustain Recent Weight Loss - Phase 2

NCT02279017
View directory record Official record
Conditions
Weight Loss
Interventions
mHealth Texting for Weight Loss
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los

NCT06079658
View directory record Official record
Conditions
Obesity
Interventions
Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Conway, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)

NCT00599040
View directory record Official record
Conditions
Diabetes, Hypertension, Insulin Resistance
Interventions
The DASH diet with weight loss, The DASH diet without weight loss, Dairy diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 5, 2026, 7:37 PM EDT
Completed No phase listed Observational

Is the Cough Stress Test Equivalent to the 24 Hour Pad Test in the Assessment of Stress Incontinence?

NCT01123096
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Cough Stress Test, 24 Hour Pad Test
Procedure · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Healthy Snack on Body Weight and Composition

NCT03159689
View directory record Official record
Conditions
Overweight
Interventions
Mixed Tree Nuts, Pretzels
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years to 60 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Results available

Weight Loss in Chronic Disease Patient Population

NCT01155050
View directory record Official record
Conditions
Overweight, Obesity, Diabetes, Hypertension
Interventions
Tele-health Home Monitoring, TrestleTree Telephone Coaching, Tele-health Home Monitoring Plus Trestle Telephone Coaching
Device · Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Houma, Louisiana • Lake Charles, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 2 Interventional Results available

Reduced Carbohydrate Versus Fat in Obese Subjects

NCT00846040
View directory record Official record
Conditions
Obesity
Interventions
Reduced fat diet, Reduced carbohydrate diet, Drug: f-18 fallypride, fMRI, PET
Other · Drug · Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Phase 1Phase 2 Interventional

Omega-3 Fatty Acids in Treating Patients With Advanced Cancer Who Have Significant Weight Loss

NCT00003077
View directory record Official record
Conditions
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
Interventions
omega-3 fatty acid
Dietary Supplement
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years to 120 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2004
U.S. locations
5
States / cities
Wilmington, Delaware • Iowa City, Iowa • Manhasset, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Prevent in Underserved Populations

NCT02664064
View directory record Official record
Conditions
Prediabetes, Overweight, Obesity
Interventions
Prevent
Behavioral
Lead sponsor
Omada Health, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
3
States / cities
Los Angeles, California • San Fernando, California • Monroe, Washington
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 5, 2026, 7:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remote Weight Management Program for Obese Women

NCT05635097
View directory record Official record
Conditions
Weight Loss
Interventions
Motivational Interviewing counseling on the Mediterranean diet and weight checks at regular intervals
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Sep 5, 2026, 7:37 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Study of BMF-650 in Otherwise Healthy Overweight or Obese Adult Participants

NCT07223216
View directory record Official record
Conditions
Obesity
Interventions
BMF-650
Drug
Lead sponsor
Biomea Fusion Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 7:37 PM EDT