Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2953–2976 of 10,535 matching trials from the live ClinicalTrials.gov search.
Active, not recruiting Phase 1 Interventional

CD40 Agonist and PD-1 Inhibitor in HNSCC

NCT06159621
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
PD-1inhibitor - LVGN 3616, CD 40 Agonist - LVGN 7409
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Pyruvate Dehydrogenase Complex Deficiency
Interventions
Dichloroacetate (DCA), Placebo, Genotype
Drug · Other · Genetic
Lead sponsor
Saol Therapeutics Inc
Industry
Eligibility
6 Months to 17 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
10
States / cities
Orange, California • Stanford, California • Washington D.C., District of Columbia + 7 more
Conditions
Multiple Myeloma
Interventions
Dexamethasone, Isatuximab, Lenalidomide
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Breast Cancer, Breast Cancer Stage IV, Metastatic Breast Cancer
Interventions
Ketogenic Diet, Low Carbohydrate Diet, Alpelisib, Fulvestrant, Canagliflozin
Dietary Supplement · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
9
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Conditions
Stroke, Patent Foramen Ovale, PFO
Interventions
Investigational PFO Closure Device, Standard of Care PFO Closure Device
Device
Lead sponsor
Occlutech International AB
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
27
States / cities
Phoenix, Arizona • Stanford, California • Thousand Oaks, California + 20 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0

NCT05553925
Conditions
Overweight, Obesity
Interventions
Online Weight Management Program with Coaching and Patient Navigator Support
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Training Effects on Fuel Metabolism

NCT02150889
Conditions
Healthy Subjects, Lean Trained Subjects, Overweight and Obesity
Interventions
Running Program, Yoga Program
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Using Data Science To Center Patient Perspectives in Mechanism Discovery

NCT06233968
Conditions
Posttraumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Malden, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BREATHE Free Curriculum

NCT06862050
Conditions
Smoking Cessation; Tobacco Dependence, E-Cig Use, Nicotine Dependence, Other Tobacco Product
Interventions
BREATHE Free Curriculum
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Interventions
Bortezomib, Dexamethasone, Pelareorep, Pembrolizumab
Drug · Biological
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Los Angeles, California
Conditions
Obesity, Adolescent
Interventions
Guys/Girls Opt for Activities for Life (GOAL)
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
10 Years to 14 Years
Enrollment
935 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • East Lansing, Michigan
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Diffuse Optical Monitoring With Inhaled Nitric Oxide

NCT03023449
Conditions
Stroke
Interventions
Nitric Oxide
Drug
Lead sponsor
Steven Messe
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Bladder Cancer, Cancer of the Bladder, Recurrent, Non-muscle Invasive Bladder Cancer
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
570 participants
Timeline
2019 – 2029
U.S. locations
36
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 30 more
Conditions
End Stage Renal Disease
Interventions
there is no intervention
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
3 Years to 21 Years
Enrollment
150 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Sacituzumab Govitecan, Pembrolizumab
Biological
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
16
States / cities
Mobile, Alabama • Oceanside, California • Clermont, Florida + 12 more
Conditions
Diffuse Large B-Cell Lymphoma, Chronic Lymphocytic Leukemia, Follicular Lymphoma
Interventions
ABBV-319
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
8
States / cities
Tucson, Arizona • Miami, Florida • Minneapolis, Minnesota + 5 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Music Intervention on Sleep

NCT06088810
Conditions
Dementia
Interventions
CoMPoSER intervention group, Sleep Education
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices

NCT06420687
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
Interventions
Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF, Experimental prosthesis - Wrist rotation + Multi DOF hand, Experimental prosthesis - Wrist rotation + wrist flexion + Multi DOF hand
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Shigellosis
Interventions
bacteriophage, Placebo
Biological · Other
Lead sponsor
Intralytix, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Relapsing Multiple Sclerosis (RMS)
Interventions
Ofatumumab approved dose, Ofatumumab new dose
Biological
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 100 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
61
States / cities
Birmingham, Alabama • Phoenix, Arizona • Berkeley, California + 50 more
Conditions
Fistula-in-ano, Draining Wound
Interventions
Kerecis fish skin
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Obesity
Interventions
Semaglutide, Tirzepatide, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

FaCT Trial (Facilitated Cascade Testing Trial)

NCT04613440
Conditions
BRCA1 Mutation, BRCA2 Mutation
Interventions
Family Letter (Standard of Care), Educational Video, Mailed Saliva Kit for Genetic Testing, Telephone Counseling
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
New York, New York • Durham, North Carolina • Houston, Texas
Active, not recruiting Not applicable Interventional Results available

Hypofractionated Radiotherapy for the Treatment of Cervical or Endometrial Cancer

NCT05139368
Conditions
Cervical Carcinoma, Endometrial Carcinoma
Interventions
Hypofractionated Radiation Therapy
Radiation
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah