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ClinicalTrials.gov public records Last synced Oct 19, 2026, 5:06 AM EDT

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Showing 289–312 of 1,056 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Medical University of South Carolina Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

NCT05796791
View directory record Official record
Conditions
Tobacco Use, Smoking Cessation, Nicotine Dependence
Interventions
Ketamine Hydrochloride, Motivational enhancement therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Phase 2Phase 3 Interventional

Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)

NCT05855369
View directory record Official record
Conditions
Smell Dysfunction, Olfactory Disorder, Long COVID
Interventions
Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO)
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Effect of Yohimbine on Cocaine Cue Reactivity

NCT00535002
View directory record Official record
Conditions
Cocaine Related Disorders
Interventions
Yohimbine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Phase 4 Interventional Results available

Buspirone Treatment for Marijuana Dependence

NCT00875836
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Buspirone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

SPARC Smartphone Application for the Management of Sarcoidosis-Associated Fatigue

NCT05230693
View directory record Official record
Conditions
Sarcoidosis, Fatigue
Interventions
Sarcoidosis Patient Assessment and Resource Companion App, Enhanced Standard Care
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional

CARS: Cannabis and Alcohol Reduction Study

NCT05486234
View directory record Official record
Conditions
Cannabis Use, Alcohol Use, Unspecified, Substance Use, Substance Use Disorders
Interventions
modified Approach-Avoidance Task (mAAT), which aims to modify automatic approach bias, modified Approach-Avoidance Task (mAAT) that does not aim to modify automatic approach bias.
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 17 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Phase 2 Interventional Results available

Fatty Acid Amide Hydrolase (FAAH) Inhibitor Treatment of Cannabis Use Disorder (CUD)

NCT03386487
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
PF 04457845, Placebo Oral Tablet
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
New Haven, Connecticut • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting No phase listed Observational

Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

NCT06181994
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
18
States / cities
Coral Gables, Florida • Jacksonville, Florida • Miami, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Terminated Phase 1 Interventional

Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells

NCT01783431
View directory record Official record
Conditions
Melanoma
Interventions
Poly ICLC, leukapheresis
Drug · Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

ACHIEVE Hearing Intervention Follow-Up Study

NCT05070429
View directory record Official record
Conditions
Hearing Loss, Aging
Interventions
Clinic-based audiological rehabilitative service delivery, Telehealth audiological rehabilitative service delivery
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years to 88 Years
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease

NCT01123369
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2010 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Acute Intermittent Hypoxia on Motor Learning

NCT05341466
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Acute Intermittent Hypoxia, SHAM Acute Intermittent Hypoxia
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke

NCT00721357
View directory record Official record
Conditions
Stroke
Interventions
Treadmill walking, Magnetic resonance spectroscopy
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mastoid taVNS-fMRI

NCT06518356
View directory record Official record
Conditions
Auricular Stimulation
Interventions
Transcutaneous Auricular Neurostimulation (tAN)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Active, not recruiting No phase listed Observational

Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial

NCT04565119
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
No intervention. This is an observational study.
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Active, not recruiting Not applicable Interventional

Accelerated High-Dose tDCS for Depression

NCT07226011
View directory record Official record
Conditions
Major Depression, Major Depression Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke

NCT06042179
View directory record Official record
Conditions
Stroke, Stroke, Acute, Stroke, Ischemic
Interventions
Frequent PT, Intense PT
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Not applicable Interventional Results available

Brain Stimulation For Cancer Smokers

NCT03419741
View directory record Official record
Conditions
Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
Interventions
Transcranial Magnetic Stimulation Clinical Research System
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2022 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

NCT07558265
View directory record Official record
Conditions
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Interventions
Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Ann Arbor, Michigan • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Phase 1 Interventional

Study of Intralesional Injection of M4N in Patients With Refractory Malignant Tumors of the Head and Neck

NCT00057512
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
M4N
Drug
Lead sponsor
Erimos Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multifocal HD-tDCS and Motor Function

NCT06561165
View directory record Official record
Conditions
Healthy
Interventions
Standard HD-tDCS intervention, Multifocal network targeted HD-tDCS intervention, Functional Magnetic Resonance Imaging (fMRI)
Device
Lead sponsor
University of Michigan
Other
Eligibility
65 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Quantitative Cardiac Parametric Mapping

NCT02855554
View directory record Official record
Conditions
Cardiomyopathy, Myocarditis, Ischemic Heart Disease
Interventions
Cardiac Magnetic Resonance (CMR) imaging techniques
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Completed Phase 2 Interventional Results available

Phase II Study of Docetaxel Before Degarelix in Patients With Newly Diagnosed Metastatic Prostate Cancer.

NCT03069937
View directory record Official record
Conditions
Metastatic Prostatic Adenocarcinoma
Interventions
Docetaxel, Degarelix
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Male only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 19, 2026, 5:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

NCT05816083
View directory record Official record
Conditions
Substance Use Disorders, HIV Infections
Interventions
Virtual Reality Tool
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 19, 2026, 5:06 AM EDT