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Showing 3241–3264 of 22,019 matching trials from the local directory fallback.
Conditions
Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy, Seizures
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
8 Years to 110 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2037
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Human iPSC for Repair of Vasodegenerative Vessels in Diabetic Retinopathy

NCT03403699
Conditions
Diabetes Complications, Diabetic Retinopathy
Interventions
Generation of inducible pluripotent stem cells
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 98 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting No phase listed Observational Accepts healthy volunteers

Characterization and Treatment of Adolescent Depression

NCT03388606
Conditions
Depression
Interventions
Growth Mindset
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
11 Years to 25 Years
Enrollment
4,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Denver, Colorado • Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

International PPB/DICER1 Registry

NCT03382158
Conditions
Ciliary Body Medulloepithelioma, Cystic Nephroma, DICER1 Syndrome, Embryonal Rhabdomyosarcoma, Embryonal Rhabdomyosarcoma of Cervix, Embryonal Rhabdomyosarcoma of Uterus (Diagnosis), Embryonal Rhabdomyosarcoma of Vagina (Diagnosis), Gynandroblastoma, Intracranial Sarcoma, Nasal Chondromesenchymal Hamartoma, Neuroblastoma, Nodular Hyperplasia of Thyroid, Ovarian Sarcoma, Pineoblastoma, Pituitary Cancer, Pleuropulmonary Blastoma, Renal Sarcoma, Sertoli-Leydig Cell Tumor, Thyroid Carcinoma, Wilms Tumor
Interventions
Not listed
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
0 Minutes to 100 Years
Enrollment
3,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2036
U.S. locations
1
States / cities
Minneapolis, Minnesota
Recruiting No phase listed Observational Accepts healthy volunteers

Taste Bud-Derived Stem Cells in Humans

NCT03366168
Conditions
Diabetes
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 120 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Cushing Disease, Cushing Syndrome, Cushing's Disease
Interventions
Barratt's Impulsivity Scale (BIS), Beck Depression Inventory (BDI), Cushing's QoL (Quality of Life Questionnaire), Hospital Anxiety and Depression Scale (HADS), Nottingham Health Profile (NHP), Perceived Stress Scale (PSS), Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant, State Food Craving Questionnaire-State (FCQ-S), State-Trait Anxiety Inventory (STAI), Trait Food Craving Questionnaire-Trait (FCQ-T), Visual Analogue Scale (VAS)
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
14 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Conditions
Neuroendocrine Neoplasms, Neuroendocrine Tumors, Paraganglioma, Pheochromocytoma
Interventions
Ga-68-DOTATATE, Lu-177-DOTATATE
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2033
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, Diffuse Midline Glioma, H3 K27M-Mutant
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2047
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Cellular Immunotherapy, Adoptive, Genetic Therapy, Hematopoietic Stem Cell Transplantation, Tissue Donors
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
4 Years to 120 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2050
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Diseases, Stomatognatic, Tooth, Tooth Diseases, Tooth Impaction
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
16 Years to 50 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
Vaccine + PolyICLC
Biological
Lead sponsor
Olivera Finn
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2032
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Hodgkin Disease, Leukemia-Lymphoma, Adult T-Cell, Lymphoma, Non-Hodgkin, Lymphomatoid Granulomatosis, Multiple Myeloma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
1,295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

NCT01568697
Conditions
Healthy Subjects, Healthy Volunteer, Immunosuppression, Periodontal Disease
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
7 Years to 100 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational

Inherited Reproductive Disorders

NCT01500447
Conditions
Amenorrhea, Genetic Disorder, Hypogonadism, Infertility
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
6 Weeks to 120 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina
Recruiting No phase listed Observational Accepts healthy volunteers

National Eye Institute Biorepository for Retinal Diseases

NCT01496625
Conditions
Age-Related Macular Degeneration, Diabetic Retinopathy, Retinal Disease, Retinal Vein Occlusion, Von Hippel-Lindau Syndrome
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
2 Years to 120 Years
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Paralysis, Paraplegia, Spinal Cord Injury, Tetraplegia
Interventions
IRS-8 (8-Channel implanted stimulator-telemeter)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
HHV-8, KSHV, KSHV Inflammatory Cytokine Syndrome (KICS)
Interventions
Cohort 1, Liposomal Doxorubicin, Rituximab, Standard Therapies, Valganiclovir, Zidovudine
Other · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
8 Years to 99 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Charcot Marie Tooth Disease
Interventions
Not listed
Lead sponsor
Michael Shy
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2030
U.S. locations
18
States / cities
Los Angeles, California • Palo Alto, California • Aurora, Colorado + 14 more
Recruiting No phase listed Observational Accepts healthy volunteers

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

NCT01143480
Conditions
Asthma, Atherosclerosis, Cancer, Insulin Resistance, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 100 Years
Enrollment
725 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Conditions
Autoimmune Disease, Glomerular Disease, Membranous Glomerulonephritis, Nephrotic Syndrome, Proteinuria
Interventions
Oral Cyclosporine, Rituximab Infusion
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Blood Sampling for Research Related to Sickle Cell Disease

NCT00542230
Conditions
Sickle Cell Anemia, Sickle Cell Disease, Sickle Cell Trait
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Familial Tumoral Calcinosis, Osteomalacia, Tumor Induced Osteomalcia
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
1 Day to 100 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Brain Disease, Cerebrovascular Accident, Cerebrovascular Disorder, Ischemic Attack, Transient, Vascular Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 120 Years
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland