Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:42 AM EDT

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Showing 25–48 of 2,027 matching trials from the live ClinicalTrials.gov search.
Conditions
Dementia, Alzheimer Disease, Late Onset
Interventions
Deprescribing of target anticholinergics, Usual Care
Other
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Indianapolis, Indiana
Conditions
Non-Pharmacological Pain Management
Interventions
Non-pharmacological Options in post-operative Hospital and Rehabilitative Management (NOHARM)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
6
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Mankato, Minnesota + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Choline and Cardiometabolic Health

NCT04764162
Conditions
Cardiovascular Risk Factor
Interventions
Choline, Placebo
Dietary Supplement
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 79 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Blacksburg, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

PACT: Providers and Alzheimer's Caregivers Together

NCT00182897
Conditions
Alzheimer's Disease, Dementia
Interventions
Skills Building for Caregiver Health and Care-recipient
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Pressure Ulcer, Pressure Injury, Wheelchair
Interventions
Sensoria, AW-Shift
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Atlanta, Georgia • Minneapolis, Minnesota • Rochester, Minnesota + 1 more
Completed Not applicable Interventional Results available

NUDGE-EHR Replication Trial at Mass General Brigham

NCT05538065
Conditions
Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction, Adverse Drug Event
Interventions
Follow-up booster Alert, Pre-commitment, Enhanced Alert
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Interventions
Zoledronic acid, vitamin D, calcium, Saline
Drug · Dietary Supplement · Other
Lead sponsor
Susan L. Greenspan
Other
Eligibility
65 Years and older · Female only
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
New Kensington, Pennsylvania
Conditions
Late Onset Alzheimer Disease
Interventions
BAY 94-9172 (Florbetaben)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
65 Years and older
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Recruiting No phase listed Observational Accepts healthy volunteers

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

NCT07099053
Conditions
Aging
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 110 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Dementia
Interventions
Aliviado Dementia Care-Hospice Edition QAPI program, Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
44,143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Depression in Old Age
Interventions
APS Treatment as Usual, Intervention-Behavioral Activation (BA)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Imaging Tau in Alzheimer's Disease and Normal Aging

NCT02884492
Conditions
Alzheimer's Disease
Interventions
18F-THK-5351, Lumbar Puncture (optional)
Drug · Procedure
Lead sponsor
William Charles Kreisl
Other
Eligibility
50 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Resilience, Aging
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Durham, North Carolina
Conditions
Hot Flashes, Menopause, Vasomotor Disturbance
Interventions
Low-dose 17-ß-estradiol with progesterone taper, Venlafaxine XR, Placebo
Drug
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years to 62 Years · Female only
Enrollment
339 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
4
States / cities
Boston, Massachusetts • Chestnut Hill, Massachusetts • Philadelphia, Pennsylvania + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ambient Independence Measures for Guiding Care Transitions

NCT02566239
Conditions
Aging
Interventions
Share activity data with care team
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
70 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Completed Phase 2 Interventional Results available

Hepatocyte Growth Factor to Improve Functioning in PAD

NCT03363165
Conditions
Peripheral Artery Disease
Interventions
VM202, Placebo
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Atherosclerosis, Cardiovascular Disease, Vascular Diseases
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
30 Years and older
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2017
U.S. locations
2
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

Technology and Family Thriving Study

NCT05150990
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life, Mental Health Wellness 1, Loneliness, Family Relationship
Interventions
Virtual Reality, Video Chat
Behavioral
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Calabasas, California • Camarillo, California • Goleta, California + 16 more
Conditions
Pain, Depressive Symptoms, Frailty, Aging
Interventions
DAPPER
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Inflammation, Cognitive Deterioration
Interventions
rhLactoferrin, Placebo
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

MOWI Research Pilot

NCT03104192
Conditions
Obesity
Interventions
Develop & Refine MOWI w/o Amulet, MOWI Weight Loss Maintenance, Develop & Refine MOWI w Fitbit, Develop & Refine MOWI w Fitbit/Protein
Behavioral · Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Recruiting Not applicable Interventional

The ROAMM-EHR Study

NCT06263322
Conditions
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Interventions
Actionable remotely generated health data, Non-Actionable remotely generated health data
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Results available

Alzheimer's in Long-Term Care--Treatment for Agitation

NCT00161473
Conditions
Alzheimer Disease, Psychomotor Agitation
Interventions
prazosin, placebo (inert substance)
Drug
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Sleep and Circadian Treatments for Shift Workers

NCT03813654
Conditions
Shift-Work Sleep Disorder, Shift-Work Related Sleep Disturbance
Interventions
8-h Afternoon-Evening Sleep, 8-h Free Sleep
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts