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ClinicalTrials.gov public records Last synced Oct 10, 2026, 9:53 AM EDT

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Showing 49–72 of 589 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University of California, Irvine Clear all
Completed Not applicable Interventional

Patient Centered Quality Reporting

NCT02738320
View directory record Official record
Conditions
Quality Report Cards
Interventions
NHCPlus
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
50 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 10, 2026, 9:53 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Metformin in Alzheimer's Dementia Prevention

NCT04098666
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Placebo oral tablet, extended release metformin
Drug
Lead sponsor
Columbia University
Other
Eligibility
55 Years to 90 Years
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
22
States / cities
Irvine, California • Palo Alto, California • Washington D.C., District of Columbia + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Withdrawn No phase listed Observational

Optical Coherence Tomography of Airway and Pleural Disorders

NCT00580892
View directory record Official record
Conditions
Disorder of Pleura and Pleural Cavity
Interventions
Optical Coherence Tomography imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Not applicable Interventional

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

NCT07073807
View directory record Official record
Conditions
Cancer, Neoplasms
Interventions
SMART Intervention using TAPPT® for Adherence, Symptom, Financial, and Social Needs Monitoring
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Irvine, California • Newport Beach, California • Orange, California + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurological Surgery & Affiliated Services De-Identified Clinical Outcomes Database

NCT00593411
View directory record Official record
Conditions
Central Nervous System Disorder, Spine Disease, Peripheral Nerve Disorder
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
7 Years and older
Enrollment
732 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting No phase listed Observational

PilotStudyAssessSafeActiveSurveillancApproachLocalThe Pa w/BrainMetsUndergoinCNSPenetratSystemicThe

NCT07827001
View directory record Official record
Conditions
Brain Cancer, Brain Cancer Metastatic, Nervous System Cancer, CNS Cancer
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Not applicable Interventional Results available

Radial Artery Access With Ultrasound Trial

NCT01605292
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Ultrasound guidance, Palpation
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
698 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Long Beach, California • Orange, California • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting Early Phase 1 Interventional

Nerve Block for Severe Abdominal Pain in the Emergency Department

NCT07826936
View directory record Official record
Conditions
Erector Spinae Plane Block
Interventions
Bupivacaine (erector spinae plane block)
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Energy Devices for Rejuvenation

NCT03767972
View directory record Official record
Conditions
Rejuvenation
Interventions
Energy-based device
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Not applicable Interventional Results available

To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients

NCT02410629
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Music Glove, Conventional Hand Exercise Program
Device · Other
Lead sponsor
David Reinkensmeyer
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Positive Affect Treatment for Adolescents With Early Life Adversity

NCT06273137
View directory record Official record
Conditions
Depression
Interventions
Positive affect treatment, Supportive psychotherapy (SUP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
12 Years to 16 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Not applicable Interventional Results available

In Vivo nCLE Study in the Pancreas With Endosonography of Cystic Tumors

NCT01236300
View directory record Official record
Conditions
Pancreatic Cysts
Interventions
Cellvizio needle-based Confocal Laser Endomicroscopy (nCLE) system
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting Not applicable Interventional

Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis

NCT05844865
View directory record Official record
Conditions
Peritoneal Carcinomatosis, Gastrointestinal Peritoneal Carcinomatosis
Interventions
Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples)
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Combined MRI and Optical Imaging to Improved Breast Cancer Diagnosis

NCT00610467
View directory record Official record
Conditions
Breast Cancer
Interventions
Disease Group, Control Group
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
21 Years to 90 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2017
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Marketability of a Technology-based Intervention to Increase HPV Vaccination

NCT03497936
View directory record Official record
Conditions
Human Papilloma Virus
Interventions
Women's Stories
Behavioral
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
18 Years to 26 Years · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
7
States / cities
Irvine, California • Chicago, Illinois • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 10, 2026, 9:53 AM EDT
Terminated Phase 2 Interventional Results available

Evaluation of Oxaliplatin and Gemcitabine in Patients With Metastatic Bladder Cancer

NCT04039867
View directory record Official record
Conditions
Carcinoma, Transitional Cell
Interventions
Oxaliplatin with Gemcitabine
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Phase 2 Interventional Results available

Chemoprevention Trial - Anastrozole in Ductal Carcinoma In Situ (DCIS) in Postmenopausal Women

NCT00256217
View directory record Official record
Conditions
DCIS
Interventions
Anastrozole
Drug
Lead sponsor
Rita Sanghvi, Mehta
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2018
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting Phase 4 Interventional

Decolonization to Reduce After-Surgery Events of Surgical Site Infection

NCT05586776
View directory record Official record
Conditions
Surgical Site Infection
Interventions
4% Chlorhexidine Gluconate, 2% Mupirocin, Soap Without Antiseptic Properties (Placebo), Placebo Nasal Ointment
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
2,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Newport Beach, California • Orange, California • Sacramento, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Breast Tumor Oxygenation During Exercise

NCT02340468
View directory record Official record
Conditions
Breast Tumor
Interventions
diffuse optical spectroscopy
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
21 Years to 70 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 10, 2026, 9:53 AM EDT
Recruiting Phase 3 Interventional

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

NCT05615844
View directory record Official record
Conditions
Open tíbia Fracture
Interventions
Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy
Drug · Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
30
States / cities
Chandler, Arizona • Tucson, Arizona • Davis, California + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Phase 4 Interventional Results available

Comparing Post-Op Narcotic Usage in Patients Receiving Periarticular Exparel vs. Standard Periarticular Joint Inj

NCT02682498
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
(Bupivacaine Liposome Injectable Suspension), Standard Preparation
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 10, 2026, 9:53 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Fractional Resurfacing Device for Treatment of Acne Scarring

NCT00585286
View directory record Official record
Conditions
Acne, Scar
Interventions
10,600 nm fractional carbon dioxide laser system
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Oct 10, 2026, 9:53 AM EDT
Not listed No phase listed Observational

The Clinical Impact and Outcomes of Interventional Endoscopy Procedures

NCT01492231
View directory record Official record
Conditions
Gastrointestinal Diseases
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 26, 2024 · Synced Oct 10, 2026, 9:53 AM EDT
Completed No phase listed Observational

REASON 1 Trial: Sonography in Cardiac Arrest

NCT01446471
View directory record Official record
Conditions
Cardiac Arrest, Pulseless Electrical Activity, Asystole
Interventions
Not listed
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Not listed
Enrollment
793 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
6
States / cities
Newark, Delaware • Boston, Massachusetts • Worcester, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 10, 2026, 9:53 AM EDT