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ClinicalTrials.gov public records Last synced Oct 15, 2026, 4:20 PM EDT

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Showing 721–744 of 872 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University of Iowa Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Post-Extraction Dehisced Socket - A Case Series Study

NCT02980211
View directory record Official record
Conditions
Tooth Loss
Interventions
Alveolar Ridge Reconstruction
Drug
Lead sponsor
Gustavo Avila-Ortiz DDS, MS, PhD
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate Supplementation and Muscle Blood Flow

NCT03459027
View directory record Official record
Conditions
Vasodilation, Blood Pressure, Active Hyperemia, Aging
Interventions
Super Beets, Beetroot powder
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 15, 2026, 4:20 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Antibiotic Use for ARIs in Urgent Care Clinics

NCT06144242
View directory record Official record
Conditions
Antibacterial Agents, Ambulatory Care
Interventions
Feedback on RTD metric
Behavioral
Lead sponsor
Daniel Livorsi
Other
Eligibility
21 Years to 99 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Free Time For Wellness 2+

NCT06654843
View directory record Official record
Conditions
Physical Inactivity
Interventions
Comparator Arm, Enhanced intervention arm
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
10
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

SPIROMICS Study of Early COPD Progression (SOURCE)

NCT05033990
View directory record Official record
Conditions
COPD, Early-Onset
Interventions
Not listed
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
30 Years to 55 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Results available

One-Lung Ventilation in the Morbidly Obese Patient: Comparison of Double Lumen Versus Bronchial Blockers

NCT00813176
View directory record Official record
Conditions
Obesity
Interventions
Double Lumen Endotracheal Tube, Arndt Bronchial Blocker
Device
Lead sponsor
Javier H Campos
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 4, 2018 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects

NCT00928135
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Xylitol, Hypertonic saline
Drug
Lead sponsor
Joseph Zabner
Other
Eligibility
12 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional

Treatment for Borderline Personality Disorder

NCT00055315
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Systems Training for Emotional Predictability and Problem Solving (STEPPS), Treatment As Usual (TAU)
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INcreasing Steps in PREgnancy Study

NCT05455008
View directory record Official record
Conditions
Pregnancy Related, Exercise, Sedentary Behavior, Behavior and Behavior Mechanisms
Interventions
Remotely-delivered health coaching intervention
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?

NCT02915874
View directory record Official record
Conditions
Anxiety
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
25 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 15, 2026, 4:20 PM EDT
Not listed Not applicable Interventional

Treatment Study of AV Node Reentry Tachycardia

NCT04232371
View directory record Official record
Conditions
Supraventricular Tachycardia
Interventions
New Ablation Technique, Standard Ablation Technique
Procedure
Lead sponsor
Jeffrey Moak
Other
Eligibility
Up to 21 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Hollywood, Florida • Iowa City, Iowa + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 15, 2026, 4:20 PM EDT
Active, not recruiting Phase 1 Interventional

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

NCT03173976
View directory record Official record
Conditions
Chondrosarcoma
Interventions
Zoledronic Acid
Drug
Lead sponsor
Mohammed Milhem
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 15, 2026, 4:20 PM EDT
Active, not recruiting Phase 3 Interventional Results available

Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

NCT00999609
View directory record Official record
Conditions
Inherited Retinal Dystrophy Due to RPE65 Mutations, Leber Congenital Amaurosis
Interventions
AAV2-hRPE65v2,voretigene neparvovec-rzyl
Biological
Lead sponsor
Spark Therapeutics, Inc.
Industry
Eligibility
3 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2030
U.S. locations
2
States / cities
Iowa City, Iowa • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting No phase listed Observational

The Effects of the CF Carrier State on the Kidneys and Pancreas

NCT05474417
View directory record Official record
Conditions
Carrier State, Pancreatic Disease, Kidney Diseases
Interventions
Not listed
Lead sponsor
Philip Polgreen
Other
Eligibility
18 Years to 100 Years
Enrollment
1,250 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

To Evaluate if the Medication Gabapentin Lessens Vulvar Pain

NCT00390013
View directory record Official record
Conditions
Vulvar Pain Symptoms, Vulvodynia (Chronic Vulvar Pain)
Interventions
Gabapentin, Placebo oral capsule
Drug
Lead sponsor
Colleen Stockdale
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Results available

Brief Behavioral Intervention for Comorbid Migraine and Depression

NCT01775852
View directory record Official record
Conditions
Migraine, Depression
Interventions
ACT-IM
Behavioral
Lead sponsor
Lilian N. Dindo
Other
Eligibility
18 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting Not applicable Interventional

CMT Gait, Mobility, Balance - AOFAS Grant

NCT07188415
View directory record Official record
Conditions
Charcot Marie Tooth Disease (CMT)
Interventions
Ankle-foot Orthoses
Device
Lead sponsor
Bopha Chrea
Other
Eligibility
25 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
North Liberty, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD

NCT03534934
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Osteoporosis
Interventions
Vital signs, Urine Pregnancy Test, Questionnaires, Blood Test, Duel-energy X-ray absorptiometry scan, Multi-detector computed tomography, Dual-energy X-ray absorptiometry scan
Diagnostic Test · Other
Lead sponsor
Punam K Saha
Other
Eligibility
45 Years to 90 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Iowa City, Iowa • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional Results available

Dietary Nitrates and Vascular Function in Patients With Peripheral Artery Disease

NCT01983826
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Sodium Nitrate, Placebo
Dietary Supplement · Other
Lead sponsor
University of Iowa
Other
Eligibility
50 Years to 85 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Not applicable Interventional

Evaluation of a Habit-based Work-up to Support Medication Adherence

NCT06230978
View directory record Official record
Conditions
Medication Adherence, Habits
Interventions
Habit workup, Standard Medication Counseling
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Waterloo, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Aspirin Attenuates Inflammation in Human Cerebral Aneurysms

NCT01710072
View directory record Official record
Conditions
The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm
Interventions
aspirin
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 29, 2015 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting No phase listed Observational

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

NCT03981575
View directory record Official record
Conditions
Myotonic Dystrophy 1, DM1
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 70 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
10
States / cities
La Jolla, California • Los Angeles, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Blood Markers of Early Pancreas Cancer

NCT03568630
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
1,250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 15, 2026, 4:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Young Adult Smoker's Treatment Demand

NCT01569529
View directory record Official record
Conditions
Smoking Cessation
Interventions
Online advertisement
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 30 Years
Enrollment
3,070 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 15, 2026, 4:20 PM EDT