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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:20 AM EDT

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Showing 745–768 of 1,897 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Yale University Clear all
Completed Phase 1 Interventional

Ketamine for Depression and Alcohol Dependence

NCT01551329
View directory record Official record
Conditions
Depression, Alcohol Dependence
Interventions
Ketalar (ketamine)
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1

NCT00023283
View directory record Official record
Conditions
Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
Interventions
Buprenorphine
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Oct 21, 2026, 1:20 AM EDT
Terminated Phase 1 Interventional

Pilot Study Of Anti-Programmed Death Ligand-1 (Anti-PD-L1, Atezolizumab) In Asymptomatic Myeloma

NCT02784483
View directory record Official record
Conditions
Asymptomatic Myeloma
Interventions
Atezolizumab (1200mg via IV infusion)
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Not applicable Interventional

Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorder

NCT01691066
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Infant Toddler Years PRT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Months to 15 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 26, 2020 · Synced Oct 21, 2026, 1:20 AM EDT
Recruiting Phase 4 Interventional

Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema

NCT07095361
View directory record Official record
Conditions
Pleural Infection Bacterial, Pleural Infections, Pleural Infections and Inflammations, Empyema, Pleural, Empyema, Complicated Pleural Effusion/ Empyema, Pleural Effusion Associated With Pulmonary Infection, Pleural Effusion
Interventions
Fibrinolytic once daily, Fibrinolytic twice daily, DNA degradation once daily, DNA degradation twice daily
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
11
States / cities
Little Rock, Arkansas • Palo Alto, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 2 Interventional Results available

Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

NCT02979977
View directory record Official record
Conditions
Squamous Cell Cancers of the Head and Neck
Interventions
cetuximab, afatinib
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Not applicable Interventional

Neurofeedback for Tourette Syndrome

NCT01702077
View directory record Official record
Conditions
Tourette Syndrome, Chronic Tic Disorder
Interventions
Neurofeedback, Sham feedback
Procedure
Lead sponsor
Yale University
Other
Eligibility
11 Years to 19 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 2 Interventional Results available

Memantine Treatment Study of Pathological Gambling

NCT00585169
View directory record Official record
Conditions
Pathological Gambling
Interventions
Memantine Hydrochloride
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Oct 21, 2026, 1:20 AM EDT
Enrolling by invitation Not applicable Interventional

LDART for Alcohol Use Disorder

NCT07221383
View directory record Official record
Conditions
Alcohol Use Disorder, Hazardous Alcohol Use
Interventions
LDART, Psychoeducational control
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes

NCT03356457
View directory record Official record
Conditions
Hyperglycaemia (Diabetic)
Interventions
Dichloroacetate, Placebo oral capsule
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 1 Interventional

Guanfacine to Reduce Stress-Induced Cocaine/Alcohol Craving and Relapse

NCT00585754
View directory record Official record
Conditions
Cocaine Dependent, Alcohol Dependent
Interventions
Guanfacine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 1 Interventional Results available

GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight

NCT04779697
View directory record Official record
Conditions
Obesity
Interventions
GLP-1 analogue - semaglutide, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Not applicable Interventional

Cannabis Use and Relapse After One Week of Contingency Management Therapy

NCT04202146
View directory record Official record
Conditions
Cannabis Dependence
Interventions
Contingency Management + Motivational Interviewing
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness Based Therapy for Insomnia in Black Women

NCT04951466
View directory record Official record
Conditions
Insomnia
Interventions
Mindfulness-based therapy for insomnia (MBTI), Healthy lifestyle intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
25 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Orange, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Infant- Toddler Climate of Healthy Interactions for Learning and Development (I-T CHILD)

NCT05132374
View directory record Official record
Conditions
Child Development, Child Behavior, Social Skills, Infant Development
Interventions
I-T CHILD
Other
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 21, 2026, 1:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adolescents

NCT02499705
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Sucralose, Sucrose, Sucralose + maltodextrin
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
13 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 21, 2026, 1:20 AM EDT
Recruiting Not applicable Interventional

A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure

NCT06671015
View directory record Official record
Conditions
Systolic Heart Failure, Respiratory Failure
Interventions
Airvo 3
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 1 Interventional

Safety and Tolerability of AZD0530 (Saracatinib) in Alzheimer's Disease

NCT01864655
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
saracatinib, Placebo
Drug
Lead sponsor
Stephen M. Strittmatter
Other
Eligibility
50 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 21, 2026, 1:20 AM EDT
Not listed Phase 4 Interventional

Buprenorphine and Integrated HIV Care Evaluation

NCT00124358
View directory record Official record
Conditions
Opioid-Related Disorders, HIV Infections, AIDS
Interventions
Buprenorphine, Integrated HIV care and office-based opioid dependence treatment
Drug · Behavioral
Lead sponsor
The New York Academy of Medicine
Other
Eligibility
18 Years and older
Enrollment
1,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
10
States / cities
Tucson, Arizona • Oakland, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2007 · Synced Oct 21, 2026, 1:20 AM EDT
Completed Phase 2 Interventional Results available

Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders

NCT01000987
View directory record Official record
Conditions
Alcohol Reactivity
Interventions
varenicline, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Oct 21, 2026, 1:20 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Oral Dronabinol-HIV

NCT06034314
View directory record Official record
Conditions
HIV
Interventions
Dronabinol Capsules
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 21, 2026, 1:20 AM EDT
Recruiting Not applicable Interventional

PRIDE III Prison Interventions and HIV Prevention Collaboration

NCT06962033
View directory record Official record
Conditions
Hiv, Opioid Use
Interventions
Opioid Agonist Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 1:20 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Step 1: Be Aware, Anxiety Prevention Intervention

NCT07044752
View directory record Official record
Conditions
Moderate Anxiety
Interventions
Anxiety Prevention Intervention, Anxiety Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 21, 2026, 1:20 AM EDT
Completed No phase listed Observational

The Adapting Disease Specific Outcome Measures Pilot Trial for Telehealth in Myasthenia Gravis

NCT05917184
View directory record Official record
Conditions
Myasthenia Gravis
Interventions
Telehealth
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
New Haven, Connecticut • Washington D.C., District of Columbia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 21, 2026, 1:20 AM EDT