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ClinicalTrials.gov public records Last synced Oct 13, 2026, 10:45 PM EDT

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Showing 73–96 of 105 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Michael J. Fox Foundation for Parkinson's Research Clear all
Completed Not applicable Interventional Results available

Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS

NCT02549859
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation (DBS) at 60 Hz, Deep Brain Stimulation (DBS) at 130 Hz, Deep Brain Stimulation (DBS) Off (Sham)
Device
Lead sponsor
University of Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Oct 13, 2026, 10:45 PM EDT
Active, not recruiting Not applicable Interventional

Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

NCT04675398
View directory record Official record
Conditions
Parkinson Disease
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed No phase listed Observational Results available

Assessing Tele-Health Outcomes in Multiyear Extensions of PD Trials

NCT03538262
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
226 participants
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting Phase 2 Interventional

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

NCT07005180
View directory record Official record
Conditions
Parkinson Disease
Interventions
HBI-002, Vehicle (placebo)
Drug
Lead sponsor
Hillhurst Biopharmaceuticals, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Fountain Valley, California • Gainesville, Florida • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 2 Interventional Results available

A Study of TAK-071 in People With Parkinson Disease

NCT04334317
View directory record Official record
Conditions
Parkinson Disease, Healthy Participants
Interventions
TAK-071, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
40 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
21
States / cities
Garden Grove, California • Irvine, California • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 2 Interventional

Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression

NCT01141023
View directory record Official record
Conditions
Parkinson Disease
Interventions
DaTscan
Drug
Lead sponsor
Ken Marek, MD
Other
Eligibility
30 Years and older
Enrollment
952 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
21
States / cities
Birmingham, Alabama • Sun City, Arizona • La Jolla, California + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 13, 2026, 10:45 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Neuro-immune Interactome in Parkinson's Disease

NCT07026929
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
40 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Not applicable Interventional Results available

Acupuncture for Fatigue in Parkinson's Disease

NCT01360229
View directory record Official record
Conditions
Parkinsons Disease
Interventions
Acupuncture, Acupuncture to treat fatigue in Parkinson disease
Procedure · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 99 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Not applicable Interventional Results available

Optimizing Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease

NCT03883217
View directory record Official record
Conditions
Parkinson Disease
Interventions
Vibration Session, No vibration session
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 95 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

NCT03713957
View directory record Official record
Conditions
Parkinson Disease
Interventions
GRF6021, Placebo
Drug · Other
Lead sponsor
Alkahest, Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Englewood, Colorado • Doral, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 2 Interventional Results available

Phase IIa Randomized Placebo Controlled Trial: Mesenchymal Stem Cells as a Disease-modifying Therapy for Idiopathic Parkinson's Disease

NCT04506073
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Mesenchymal Stem Cells, Placebo
Drug
Lead sponsor
Mya Schiess
Other
Eligibility
50 Years to 79 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting Not applicable Interventional

A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

NCT07705373
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
MR-005 (MedRhythms, Inc., Portland, ME)
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Boston, Massachusetts • St Louis, Missouri • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 3 Interventional Results available

Carbidopa-Levodopa (CD-LD) ER Alone or in Combination With CD-LD IR to IPX066 Followed by IPX066 Extension Safety Study

NCT01411137
View directory record Official record
Conditions
Parkinson's Disease
Interventions
IPX066
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
30 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Sunnyvale, California + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting Phase 1Phase 2 Interventional

Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)

NCT07142044
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
EC5026 oral tablet, Placebo
Drug
Lead sponsor
EicOsis Human Health Inc.
Industry
Eligibility
50 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed No phase listed Observational

Long Term Follow Up KET-PD

NCT06164756
View directory record Official record
Conditions
Parkinson's Disease, Depression
Interventions
Cognitive Behavior Therapy (CBT), Treatment As Usual (TAU)
Other
Lead sponsor
Yale University
Other
Eligibility
40 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

This Protocol is a Sub-study Under the PPMI Program. It is a Longitudinal, Single-center Study to Assess the Performance of [18F]AV-133 Imaging Using High and Standard Resolution PET in Individuals Enrolled With Parkinson's Disease (PD) for up to 12 Months.

NCT07830654
View directory record Official record
Conditions
Parkinson's Disease (PD), Healthy Control Subjects
Interventions
[18F]AV-133
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson's Disease

NCT02896816
View directory record Official record
Conditions
Parkinson
Interventions
Surface EMG, MRI and PET Scan, Surface EMG
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 13, 2026, 10:45 PM EDT
Terminated Not applicable Interventional Results available

Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

NCT04598828
View directory record Official record
Conditions
Parkinson Disease
Interventions
Non-invasive brainstem stimulation
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 13, 2026, 10:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electromyography Signals as Biomarkers for Parkinson's Disease

NCT02168504
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Norconnect Inc
Industry
Eligibility
25 Years to 82 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Ogdensburg, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting Not applicable Interventional

Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease

NCT06602544
View directory record Official record
Conditions
Parkinson Disease (PD)
Interventions
Robotic Apparel
Device
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Allston, Massachusetts • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 13, 2026, 10:45 PM EDT
Active, not recruiting No phase listed Observational

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

NCT06621602
View directory record Official record
Conditions
REM Behavior Disorder, Parkinson Disease
Interventions
Not listed
Lead sponsor
CND Life Sciences
Other
Eligibility
50 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
18
States / cities
Scottsdale, Arizona • Aliso Viejo, California • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Completed Phase 2 Interventional

Phase IIb Study of Intranasal Glutathione in Parkinson's Disease

NCT02424708
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Reduced Glutathione 100mg, Reduced Glutathione 200mg, Placebo
Drug
Lead sponsor
Bastyr University
Other
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Kenmore, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2016 · Synced Oct 13, 2026, 10:45 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

NCT04477785
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
30 Years and older
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2033
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 13, 2026, 10:45 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Spectroscopy in Parkinson Disease

NCT01005030
View directory record Official record
Conditions
Parkinson Disease
Interventions
Blood draw
Other
Lead sponsor
Molecular Biometrics, Inc.
Industry
Eligibility
46 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 10, 2009 · Synced Oct 13, 2026, 10:45 PM EDT