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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:44 AM EDT

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Showing 1273–1296 of 1,571 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Wake Forest University Clear all
Completed No phase listed Observational

Symptom Burden and Unmet Supportive Care Needs in Lung Cancer Patients Undergoing First or Second Line Immunotherapy

NCT03741868
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2020 · Synced Oct 17, 2026, 6:44 AM EDT
Recruiting Not applicable Interventional

E-PRIME For Children With Medical Complexity

NCT06216548
View directory record Official record
Conditions
Children With Medical Complexity
Interventions
Usual Care and Enhanced Primary Care, Enhanced Primary Care
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 17 Years
Enrollment
909 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The PATHway Study: Primary Care Based Depression Prevention in Adolescents

NCT05203198
View directory record Official record
Conditions
Depression, Mental Disorder in Adolescence
Interventions
Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Chicago, Illinois • Glenview, Illinois • Park Ridge, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Active, not recruiting Not applicable Interventional

The Arteriovenous Vascular (AV) ACCESS Trial

NCT04646226
View directory record Official record
Conditions
End-Stage Kidney Disease, Hemodialysis Complication
Interventions
AV graft, surgical intervention for creation of a fistula
Device · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
7
States / cities
Birmingham, Alabama • Los Angeles, California • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Phase 3 Interventional

Chemotherapy and Radiation Therapy With or Without Epoetin Alfa in Treating Patients With Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer

NCT00028938
View directory record Official record
Conditions
Lung Cancer
Interventions
epoetin alfa, carboplatin, paclitaxel, radiation therapy
Biological · Drug · Radiation
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease

NCT03740048
View directory record Official record
Conditions
End Stage Renal Failure on Dialysis
Interventions
Hemodialysis, Patiromer Oral Product
Other · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parents and Children Together Preventing Diabetes (PACT PD)

NCT01819493
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Lifestyle Intervention, Standard Family-Based intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
8 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 17, 2026, 6:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

COVID-19 IgG Formation in Physicians at ALGH and Their Household Members

NCT04540484
View directory record Official record
Conditions
Covid19, SARS-CoV Infection, Communicable Disease
Interventions
Screening
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional

Effect of Intense vs. Standard Hypertension Management on Nighttime Blood Pressure - an Ancillary Study to SPRINT

NCT01835249
View directory record Official record
Conditions
Hypertension
Interventions
Intensive BP Arm, Standard BP arm
Other
Lead sponsor
University of Minnesota
Other
Eligibility
55 Months and older
Enrollment
897 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
10
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Jacksonville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2019 · Synced Oct 17, 2026, 6:44 AM EDT
Recruiting Not applicable Interventional

Incremental Hemodialysis: The TwoPlus Trial

NCT05828823
View directory record Official record
Conditions
End-Stage Kidney Disease
Interventions
Hemodialysis twice weekly, Hemodialysis thrice weekly
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
10
States / cities
Jacksonville, Florida • Atlanta, Georgia • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Completed No phase listed Observational

RUral dispaRities in prehospitAL STEMI

NCT04381260
View directory record Official record
Conditions
ST Elevation Myocardial Infarction, Cardiovascular Diseases
Interventions
No intervention, Interview, Survey
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
473 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery

NCT03048682
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
Interventions
Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Weston, Florida • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

Incentives to Decrease Opioid Use - Pilot

NCT04235582
View directory record Official record
Conditions
Substance-Related Disorders, Opioid-Related Disorders, Behavior Therapy
Interventions
App + Inputs Contingency Management, App + Outcomes Contingency Management
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Berkeley, California • Chicago, Illinois • Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Phase 2 Interventional Results available

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

NCT00721513
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
cetuximab, cisplatin, docetaxel, fluorouracil, computed tomography, positron emission tomography, quality-of-life assessment, 3-dimensional conformal radiation therapy, intensity-modulated radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 17, 2026, 6:44 AM EDT
Active, not recruiting No phase listed Observational

IORT-Breast at Medical Center Navicent Health

NCT04595435
View directory record Official record
Conditions
Breast Cancer Female, Early-stage Breast Cancer
Interventions
Lumpectomy, Intraoperative Radiation Therapy
Procedure · Radiation
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2033
U.S. locations
1
States / cities
Macon, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Recruiting Phase 2 Interventional

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

NCT07291297
View directory record Official record
Conditions
Sarcoma Metastatic, Sarcoma, Soft Tissue
Interventions
Metformin Hydrochloride ER
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Terminated No phase listed Observational

Adaptation of an eHealth (Web-application) Platform for Delivery of a Sedentary Behavior Intervention Among Prostate Cancer Patients

NCT03740035
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
eHealth for Sedentary Behavior
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Male only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Brimonidine

NCT03959176
View directory record Official record
Conditions
Intraocular Pressure
Interventions
Brimonidine, Tropicamide, Phenylephrine Ophthalmic Product
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional

ICOLLAB FOR Children With Medical Complexity

NCT03978468
View directory record Official record
Conditions
Children With Medical Complexity
Interventions
Interagency Collaboration (ICollab), Usual Care
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 17 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 17, 2026, 6:44 AM EDT
Recruiting Not applicable Interventional

Geriatric Distal Femur

NCT07237191
View directory record Official record
Conditions
Articular Fractures
Interventions
Single Implant Fixation, Dual Implant Fixation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 17, 2026, 6:44 AM EDT
Completed No phase listed Observational

Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

NCT00499798
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity, Infertility
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Rectal Indomethacin in the Prevention of Post-ERCP Pancreatitis

NCT01912716
View directory record Official record
Conditions
Post-ERCP Pancreatitis
Interventions
high dose indomethacin, standard dose indomethacin
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
1,037 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
6
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Ann Arbor, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of an mHealth Colorectal Cancer Screening Intervention

NCT02088333
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
mCRC intervention, Healthy Lifestyles video
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 74 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
6
States / cities
Advance, North Carolina • Mount Airy, North Carolina • Wilkesboro, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Oct 17, 2026, 6:44 AM EDT
Completed Not applicable Interventional Results available

Relaxing Environment to Lower Anxiety During Onabotulinum Toxin Chemodenervation of the Bladder

NCT06319898
View directory record Official record
Conditions
Anxiety, Pain, Burnout, Professional
Interventions
Lavender aromatherapy sticker
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Oct 17, 2026, 6:44 AM EDT