Independent directory Public ClinicalTrials.gov records United States
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Showing 145–168 of 872 matching trials from the live ClinicalTrials.gov search.
Active, not recruiting Not applicable Interventional

Cystoealstometer (Bladder Monitor Device)-Home Use

NCT05232253
Conditions
Urinary Bladder, Neurogenic
Interventions
Cystoelastometer - Urodynamics Testing
Device
Lead sponsor
University of Iowa
Other
Eligibility
6 Months to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Pancreatitis, Chronic, Pancreatitis, Acute
Interventions
Blood sample, Patient questionnaires, Saliva sample, Urine sample
Diagnostic Test · Behavioral
Lead sponsor
Aliye Uc
Other
Eligibility
0 Years to 17 Years
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
18
States / cities
Beverly Hills, California • Los Angeles, California • San Francisco, California + 15 more
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Anxiety-mediated Impairments in Large Elastic Artery Function and the Autonomic Nervous System

NCT03109795
Conditions
Anxiety, Hypertension
Interventions
Clonidine Pill, Hydrochlorothiazide
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 79 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Urethral Stricture
Interventions
Ventral buccal mucosa onlay urethroplasty, Dorsal buccal mucosa onlay urethroplasty
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Completed Phase 4 Interventional Results available

ECMO Hemostatic Transfusions in Children

NCT05796557
Conditions
Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Thromboembolism, Transfusion Adverse Reaction
Interventions
Platelet Transfusion
Biological
Lead sponsor
Yale University
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Atlanta, Georgia • Iowa City, Iowa • Louisville, Kentucky + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Visualizing Dermal Micropores With OCT

NCT04867733
Conditions
Healthy
Interventions
Micropatch (microneedle patch)
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Withdrawn Not applicable Interventional

Intradural Percutaneous Stimulation

NCT03380104
Conditions
Pain, Chronic
Interventions
Intradural Spinal Cord Stimulation, Administration of Questionnaires
Device · Behavioral
Lead sponsor
Matthew Howard
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Diabetes Mellitus, Hypertension, Coronary Artery Disease, Atrial Fibrillation, Stroke
Interventions
PHCVRS Intervention, Personal Health Record
Other
Lead sponsor
Korey Kennelty
Other
Eligibility
50 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
12
States / cities
Akron, Iowa • Belmond, Iowa • Cedar Rapids, Iowa + 9 more
Conditions
Type 2 Diabetic Peripheral Neuropathy (DPN)
Interventions
Metanx (a medical food), Metanx placebo
Other
Lead sponsor
Pamlab, Inc.
Industry
Eligibility
25 Years to 80 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
6
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Omaha, Nebraska + 3 more
Conditions
Multiple Myeloma
Interventions
Sirolimus, Teclistamab, Talquetamb
Drug · Biological
Lead sponsor
Christopher Strouse
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Schizophrenia, Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions
High-resolution fMRI during working memory, cognitive control, and decision-making tasks
Other
Lead sponsor
Kai Hwang
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Repeatability in Hyperpolarized 3-Helium With MRI

NCT03776747
Conditions
Radiation Exposure
Interventions
Prone hyperpolarized 3 helium gas scan, Supine hyperpolarized 3 helium gas scan, Vitals, Pulmonary Function Tests, Initial protocol MRI scan
Drug · Diagnostic Test
Lead sponsor
Eric A. Hoffman
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Primary Glioblastoma Multiforme
Interventions
Gliadel Wafer, Temodar and Radiotherapy
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Control Functions of the Human Thalamus

NCT06920992
Conditions
Stroke
Interventions
measuring cognitive flexibility including working memory and set-switching
Behavioral
Lead sponsor
Kai Hwang
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Adult Medulloblastoma, Childhood Medulloblastoma, Neuroblastoma, Neuroendocrine Tumor, Somatostatinoma
Interventions
gallium Ga 68-edotreotide, positron emission tomography/computed tomography, indium In 111 pentetreotide, computed tomography, contrast-enhanced magnetic resonance imaging
Drug · Procedure · Radiation
Lead sponsor
Sue O'Dorisio
Other
Eligibility
2 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Terminated Phase 2Phase 3 Interventional Results available

Targeting Vascular Reactivity in Idiopathic Pulmonary Fibrosis

NCT00981747
Conditions
Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis
Interventions
Sildenafil, Losartan, Sildenafil and Losartan, Placebo Oral Tablet
Drug
Lead sponsor
Alicia Gerke
Other
Eligibility
18 Years to 99 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Terminated Phase 2 Interventional Results available

NR in Chemo-induced Peripheral Neuropathy

NCT03642990
Conditions
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Metastatic, Platinum-resistant Recurrent Ovarian Cancer, Head and Neck Cancer Stage IV, Endometrial Cancer Stage IV
Interventions
Nicotinamide Riboside
Drug
Lead sponsor
Donna Hammond, PhD
Other
Eligibility
18 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Iowa City, Iowa • Winston-Salem, North Carolina
Conditions
Tinnitus
Interventions
TMS for tinnitus
Device
Lead sponsor
Aaron Boes
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Obesity, Knee Osteoarthritis
Interventions
InBody Band 2
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Idiopathic Subglottic Stenosis (iSGS)
Interventions
Endoscopic dilation of subglottic stenosis, Endoscopic resection of the stenosis, Tracheal Resection
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
39
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Irvine, California + 35 more
Conditions
Inflammatory Abdominal Aortic Aneurysm, Aneurysm, Infected, Aneurysm, Mycotic, Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Interventions
Complex endovascular aortic repair (cEVAR)
Procedure
Lead sponsor
CEVARII
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Quality of Life, IVF, Patient Satisfaction, Patient Engagement, Patient Empowerment
Interventions
CALM IVF, Standard of Care
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Gestational Diabetes, Endothelial Dysfunction, Physical Inactivity
Interventions
Insulin aspart
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Pancreatic Neoplasms
Interventions
Ascorbate, Gemcitabine, Radiation therapy
Drug · Radiation
Lead sponsor
Joseph J. Cullen
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa