Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:49 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2257–2280 of 10,535 matching trials from the live ClinicalTrials.gov search.
Conditions
Prostate Cancer, Oligometastatic Disease
Interventions
niraparib/abiraterone acetate, Stereotactic ablative radiation therapy (SABR), Androgen deprivation therapy (ADT)
Drug · Radiation
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Cancer, Major Depressive Disorder
Interventions
Psilocybin, Placebo
Drug
Lead sponsor
Sunstone Medical
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Osteoarthritis, Knee
Interventions
Zero Degree Knee Positioner
Device
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
40 Years to 80 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Breast Cancer, Cancer Survivor
Interventions
educational intervention, counseling intervention, standard follow-up care, quality-of-life assessment, questionnaire administration
Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
2
States / cities
Duarte, California • Lancaster, California
Conditions
Physical Disability
Interventions
Virtually supervised exercise, Health education
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 100 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of OLX-07010 in Healthy Adult and Elderly Participants

NCT05696483
Conditions
Alzheimer Disease
Interventions
OLX-07010 Active, OLX-07010 Placebo
Drug
Lead sponsor
Oligomerix, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Glendale, California
Conditions
Fabry Disease, Fabry Disease, Cardiac Variant
Interventions
ST-920
Biological
Lead sponsor
Sangamo Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2039
U.S. locations
8
States / cities
Irvine, California • Tampa, Florida • Atlanta, Georgia + 5 more
Conditions
Malignant Pleural Mesothelioma
Interventions
Pembrolizumab, IMPRINT
Drug · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence

NCT06721351
Conditions
Diabetic Retinopathy (DR)
Interventions
Diabetic Retinopathy screening Point of Care Artificial Intelligence
Diagnostic Test
Lead sponsor
Centro De Salud La Comunidad De San Ysidro Inc DBA: San Ysidro Health
Other
Eligibility
22 Years and older
Enrollment
548 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
3
States / cities
Chula Vista, California • San Diego, California
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Bridge-Enhanced ACL Restoration (BEAR)
Device
Lead sponsor
Miach Orthopaedics
Industry
Eligibility
12 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2034
U.S. locations
11
States / cities
San Diego, California • Tampa, Florida • Atlanta, Georgia + 8 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Olive Oil Polyphenols and Cardiovascular Health Biomarkers

NCT04149288
Conditions
Healthy, Normal Weight, Overweight, Obese
Interventions
High-polyphenol olive oil, Low-polyphenol olive oil
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
20 Years to 45 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Davis, California
Conditions
Spinal Cord Injuries
Interventions
High Dose Intervention-tsDCS, Low Dose Intervention-tsDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Advanced Solid Tumor, Metastatic Solid Tumors
Interventions
Raludotatug deruxtecan
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
8
States / cities
Marietta, Georgia • Ann Arbor, Michigan • East Brunswick, New Jersey + 5 more
Conditions
Endogenous Cushing's Syndrome
Interventions
Osilodrostat
Drug
Lead sponsor
RECORDATI GROUP
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
15
States / cities
Phoenix, Arizona • Atlanta, Georgia • Chicago, Illinois + 11 more
Conditions
Wilson Disease
Interventions
Not listed
Lead sponsor
Prime Medicine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
7
States / cities
Los Angeles, California • Sacramento, California • New Haven, Connecticut + 4 more
Conditions
Ovarian Cancer
Interventions
olaparib, paclitaxel, carboplatin, Drug: carboplatin
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 125 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2026
U.S. locations
8
States / cities
Stanford, California • West Hollywood, California • Orlando, Florida + 4 more
Conditions
Bladder Cancer
Interventions
TAR-200, Cetrelimab, BCG Vesiculture
Drug · Biological
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years and older
Enrollment
1,135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
51
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Long Beach, California + 42 more
Conditions
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Interventions
Biopsy Procedure, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Panitumumab, Sotorasib
Procedure · Biological · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
180
States / cities
Birmingham, Alabama • Mobile, Alabama • Los Angeles, California + 135 more
Conditions
Glioblastoma
Interventions
INO-5401, INO-9012, Cemiplimab, Radiation Therapy, Temozolomide
Biological · Radiation · Drug
Lead sponsor
Inovio Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
21
States / cities
Duarte, California • Palo Alto, California • San Francisco, California + 15 more
Conditions
Diabetic Macular Edema
Interventions
PDS Implant Pre-Filled with 100 mg/mL Ranibizumab, Intravitreal Ranibizumab 0.5 mg Injection, Ranibizumab refill exchange
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
89
States / cities
Mesa, Arizona • Phoenix, Arizona • Bakersfield, California + 79 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of the Cortex and Spinal Cord

NCT06586437
Conditions
Cerebral Palsy
Interventions
Clinical Assessments, Brain-Spinal Cord fMRI, Hoffmann Reflex Assessments, MEG Imaging, Transcutaneous Current Stimulation
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
11 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boys Town, Nebraska
Active, not recruiting Not applicable Interventional Results available

LIFE-BTK PK Sub-study

NCT05208905
Conditions
Critical Limb Ischemia (CLI)
Interventions
Esprit BTK Device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Jacksonville, Florida • South Dartmouth, Massachusetts • Bartlesville, Oklahoma
Conditions
Recurrent Cervix Cancer, Progressive Cervix Cancer
Interventions
Niraparib, dostarlimab
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
4
States / cities
Indianapolis, Indiana • New Orleans, Louisiana • Oklahoma City, Oklahoma + 1 more
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Evaluating the Human Immune Response to the JYNNEOS Vaccine

NCT06366672
Conditions
Vaccinia, Virus Diseases
Interventions
JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, Phlebotomy, Research bronchoscopy, Skin punch biopsy, Bone marrow aspiration
Biological · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri