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ClinicalTrials.gov public records Last synced Oct 4, 2026, 5:01 PM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Carolina Musculoskeletal Institute Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®

NCT00933998
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Metanx® (Oral L-methylfolate, Methylcobalamin and Pyridoxal 5'-phosphate)
Other
Lead sponsor
Carolina Musculoskeletal Institute
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Aiken, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia

NCT00523302
View directory record Official record
Conditions
Major Depression, Fibromyalgia
Interventions
Active TMS, Sham TMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Internet-Based Osteoarthritis Pain Coping Skills Intervention

NCT01638871
View directory record Official record
Conditions
Osteoarthritis
Interventions
PainCOACH
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Durham, North Carolina • Smithfield, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

OA Clinic-Community CARE Model

NCT05349500
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity, Physical Inactivity, Weight Loss
Interventions
OA CARE Intervention, Usual Care control group
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention to Improve Quality of Life in African American Lupus Patients

NCT01837875
View directory record Official record
Conditions
Depression, Systemic Lupus Erythematosus
Interventions
Chronic Disease Self-Management Program (CDSMP), Mail-delivered arthritis kit, Support group, Listserv
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Risk Factors for Anterior Cruciate Ligament (ACL) Injury

NCT00124319
View directory record Official record
Conditions
Knee Injuries, Athletic Injuries
Interventions
Not listed
Lead sponsor
Steve Marshall
Other
Eligibility
18 Years and older
Enrollment
4,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
3
States / cities
Colorado Springs, Colorado • Annapolis, Maryland • West Point, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Oct 4, 2026, 5:01 PM EDT
Completed No phase listed Observational

Antiphospholipid Syndrome Collaborative Registry (APSCORE)

NCT00076713
View directory record Official record
Conditions
Antiphospholipid Syndrome
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
7
States / cities
Atlanta, Georgia • Baltimore, Maryland • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

CCCR Lupus Patient Navigator Program

NCT04461158
View directory record Official record
Conditions
Systemic Lupus Erythematosus (SLE)
Interventions
Patient Navigator Services
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 4, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

Virtual Reality Mindfulness Meditation After ACL Reconstruction

NCT05527171
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
Virtual Reality Mindfulness Meditation, Virtual Reality Sham
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 25 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 2 Interventional

Improving Quality of Life for African American Female Adolescents With Lupus

NCT00068874
View directory record Official record
Conditions
Lupus
Interventions
Coping skills and cognitive restructuring techniques, Educational training
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Improving Physical Activity and Gait Symmetry After Total Knee Arthroplasty

NCT04090125
View directory record Official record
Conditions
Knee Replacement, Total, Knee Arthroplasty, Total
Interventions
PAS Intervention, Attention Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 1 Interventional

Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)

NCT00418587
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
Cholecalciferol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Systemic Lupus Erythematosus in Gullah Health

NCT00756769
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

The Effects of CBT and tDCS on Fibromyalgia Patients

NCT02723175
View directory record Official record
Conditions
Fibromyalgia, Chronic Pain
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Acceptability of PREVAIL (PREserving Valued Activities In Life)

NCT06706999
View directory record Official record
Conditions
Rheumatoid Arthritis (RA), Arthritis, Rheumatoid (RA)
Interventions
PREVAIL model of care
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 1 Interventional

Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma

NCT02426229
View directory record Official record
Conditions
Scleroderma, Interstitial Lung Disease
Interventions
dabigatran etexilate
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2018 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 1 Interventional Results available

Safety Study of Transvenous Limb Perfusion in Human Muscular Dystrophy

NCT00873782
View directory record Official record
Conditions
Muscular Dystrophies, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Limb-Girdle Muscular Dystrophy
Interventions
Retrograde high pressure transvenous perfusion with normal saline
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 2 Interventional

Oral Type I Collagen for Relieving Scleroderma

NCT00005675
View directory record Official record
Conditions
Scleroderma, Connective Tissue Diseases
Interventions
Oral bovine type I collagen, Placebo
Drug
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Farmington, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated May 25, 2010 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

The Cherokee Study: Cherokee Health for Elderly Residents With Osteoarthritis of the Knee

NCT04946344
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diet & Exercise, Attention Control
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Cherokee, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 3 Interventional Results available

Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

NCT02772965
View directory record Official record
Conditions
Pediatric Crohn's Disease
Interventions
Methotrexate, Sugar pill (placebo)
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 20 Years
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
32
States / cities
Birmingham, Alabama • Alto, California • New Haven, Connecticut + 27 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 4 Interventional Results available

The BEST Trial: Biomarkers for Evaluating Spine Treatments

NCT05396014
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM), Duloxetine
Behavioral · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
1,014 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Redwood City, California • San Diego, California • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 4, 2026, 5:01 PM EDT
Completed Phase 2 Interventional

Sensory-Targeted Ankle Rehabilitation Strategies (STARS)

NCT01541657
View directory record Official record
Conditions
Chronic Ankle Instability
Interventions
Ankle Joint Mobilization, Foot Massage, Calf Stretching
Other
Lead sponsor
Joel Thompson
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Ithaca, New York • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 26, 2018 · Synced Oct 4, 2026, 5:01 PM EDT