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ClinicalTrials.gov public records Last synced Oct 2, 2026, 5:32 AM EDT

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: MiMedx Group, Inc. Clear all
Completed Not applicable Interventional

Amniotic Membrane in Total Knee Replacements to Reduce Scarring

NCT02088567
View directory record Official record
Conditions
Scarring
Interventions
Total Knee Arthroplasty, Application of dHACM
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

An Evaluation of the Effect of the AmnioFix Amniotic Membrane Allograft in Patients Undergoing Posterior Instrumentation Removal

NCT01357187
View directory record Official record
Conditions
Adhesions of Soft Tissue
Interventions
Scheduled removal of posterior instrumentation with AmnioFix, Scheduled removal of posterior instrumentation without AmnioFix
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Reston, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis

NCT03074526
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Amniotic Fluid, Saline Placebo
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
30 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Birmingham, Alabama • Atlanta, Georgia • Des Plaines, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Phase 3 Interventional

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis

NCT03414268
View directory record Official record
Conditions
Fasciitis, Plantar
Interventions
Micronized dHACM, Saline Injection
Other · Drug
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
21 Years to 79 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
17
States / cities
Tucson, Arizona • Carlsbad, California • Carmichael, California + 14 more
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

DHACM vs Other Commercially Available Treatments

NCT01921491
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Dressing Application, Offloading
Procedure · Device
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Tulsa, Oklahoma • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers

NCT01552447
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
EpiFix, Compression Therapy
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
5
States / cities
Boca Raton, Florida • Framingham, Massachusetts • Tulsa, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Comparative Study of Amniotic Membrane Injectable in the Treatment of Recalcitrant Plantar Fasciitis

NCT01659827
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
Marcaine, 0.5cc AmnioFix, 1.25cc AmnioFix, Saline
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Roanoke, Virginia • Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers

NCT01693133
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Standard of Care: Moist Wound Therapy and Offloading, EpiFix plus Standard of Care
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
20
States / cities
Birmingham, Alabama • Bakersfield, California • Castro Valley, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Oct 2, 2026, 5:32 AM EDT
Withdrawn Not applicable Interventional

Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face

NCT01995604
View directory record Official record
Conditions
Scarring
Interventions
Application of Sterile 0.9% Saline Solution, Application of dHACM
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2014 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring

NCT02033824
View directory record Official record
Conditions
Scarring
Interventions
dHACM, Craniectomy
Other · Procedure
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Boulder, Colorado • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Use of dHACM in the Treatment of Venous Leg Ulcers

NCT02011503
View directory record Official record
Conditions
Leg Ulcer
Interventions
Multi-layer compression therapy, Application of dHACM
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
15
States / cities
Phoenix, Arizona • Carlsbad, California • Castro Valley, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2018 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers

NCT01552499
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Standard of care, Applications of EpiFix
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Timeline
2012
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

DHACM in Robotic Assisted Laparoscopic Prostatectomy (RALP)

NCT02526173
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
RALP using full nerve sparing technique, dHACM Application
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
40 Years to 70 Years · Male only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 2, 2026, 5:32 AM EDT
Terminated Not applicable Interventional

Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis

NCT01921569
View directory record Official record
Conditions
Epicondylitis, Lateral Humeral
Interventions
Standard of Care Therapy, dHACM Injection, Normal Saline Injection
Behavioral · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Sharonville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 2, 2026, 5:32 AM EDT
Terminated Phase 2 Interventional

Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis

NCT05796765
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Micronized DHACM 40 mg, Micronized DHACM 100 mg, Saline
Biological · Drug
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
14
States / cities
La Mesa, California • Miami, Florida • The Villages, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy

NCT03323021
View directory record Official record
Conditions
Partial Nephrectomy, Kidney Cancer, Renal Function Aggravated
Interventions
Dehydrated human amnion/chorion membrane, Standard of Care
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

dHACM in Lumbar Decompression and Microdiscectomy Surgery

NCT02300909
View directory record Official record
Conditions
Scarring, Spinal Stenosis, Herniated Disc
Interventions
Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Phase 2Phase 3 Interventional

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis

NCT02427191
View directory record Official record
Conditions
Fasciitis, Plantar
Interventions
AmnioFix® Injectable, Saline Injection
Other · Drug
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
21 Years to 79 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
11
States / cities
Tucson, Arizona • Fresno, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

dHACM Mesh In the Treatment of Diabetic Foot Ulcers

NCT02589210
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
EpiFix Mesh
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2017 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Evaluation of Amniotic Fluid Product in Knee Osteoarthritis

NCT02768155
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Amniotic Fluid 4.0ml dose, Amniotic Fluid 2.0ml dose, Placebo Control
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
30 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 2, 2026, 5:32 AM EDT
Terminated Not applicable Interventional

Dehydrated Human Amnion Chorion Membrane (dHACM) vs. Control in the Treatment of Partial Thickness Burns.

NCT02765737
View directory record Official record
Conditions
Treatment of Partial Thickness Burns
Interventions
Dehydrated Human Amnion/Chorion Membrane, Mepilex Ag
Other · Device
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
12 Months to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
6
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 3 more
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 2, 2026, 5:32 AM EDT
Not listed Not applicable Interventional

Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

NCT06600724
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer, Diabetic, Foot Ulcer
Interventions
Standard of Care, EPIEFFECT, EPIXPRESS
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair

NCT03084068
View directory record Official record
Conditions
Shoulder Injury, Shoulder Sprain, Supraspinatus Tear
Interventions
Human dehydrated umbilical cord allograft, Placebo
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wexford, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 2, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Randomized Clinical Trial Using Amniotic Membrane in Robotic Assisted Laparoscopic Prostatectomy

NCT01832168
View directory record Official record
Conditions
Pudendal Nerve
Interventions
Robotic Assisted Laparoscopic Prostatectomy, Application of Absorbable Hemostat, Application of dehydrated human amniotic membrane
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
45 Years to 70 Years · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 2, 2026, 5:32 AM EDT