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ClinicalTrials.gov public records Last synced Oct 9, 2026, 1:50 AM EDT

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Showing 1–24 of 105 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Michael J. Fox Foundation for Parkinson's Research Clear all
Completed Not applicable Interventional Results available

Robotic Walking Device to Improve Mobility in Parkinson's Disease

NCT03751371
View directory record Official record
Conditions
Parkinson Disease
Interventions
Training with HWA device, Usual Care
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 9, 2026, 1:50 AM EDT
Completed Phase 3 Interventional Results available

Carbidopa-Levodopa (CD-LD) ER Alone or in Combination With CD-LD IR to IPX066 Followed by IPX066 Extension Safety Study

NCT01411137
View directory record Official record
Conditions
Parkinson's Disease
Interventions
IPX066
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
30 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Sunnyvale, California + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Oct 9, 2026, 1:50 AM EDT
Completed Phase 1 Interventional

Measuring Parkinson's Disease Progression

NCT03205956
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Levodopa
Drug
Lead sponsor
Kevin J. Black, MD
Other
Eligibility
40 Years to 79 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

NCT06993142
View directory record Official record
Conditions
Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia Diseases, Central Nervous System Diseases, Synucleinopathies, Nervous System Diseases, Cerebral Disorder, Brain Diseases, Parkinsonian Disorders, Genetic Predisposition
Interventions
Increase of physical activity volume and intensity with the use of a motivational smartphone application
Behavioral
Lead sponsor
Radboud University Medical Center
Other
Eligibility
50 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Novel Measurement Concept to Objectively Quantify Severity of Vocal and Speech Related Symptoms Associated With Parkinson's Disease

NCT05421832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Digital Speech Application
Device
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 9, 2026, 1:50 AM EDT
Terminated Not applicable Interventional Results available

Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

NCT04598828
View directory record Official record
Conditions
Parkinson Disease
Interventions
Non-invasive brainstem stimulation
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 9, 2026, 1:50 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Target Engagement of Terazosin in Healthy Adults

NCT04551040
View directory record Official record
Conditions
Healthy
Interventions
Terazosin
Drug
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

FoxBioNet: ECV (Extracellular Vesicle) 004

NCT04603326
View directory record Official record
Conditions
Parkinson Disease
Interventions
Lumbar Puncture
Procedure
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
30 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
4
States / cities
Chicago, Illinois • New York, New York • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 9, 2026, 1:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson's Disease

NCT02896816
View directory record Official record
Conditions
Parkinson
Interventions
Surface EMG, MRI and PET Scan, Surface EMG
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

NCT07020026
View directory record Official record
Conditions
Parkinson's Disease
Interventions
[18F]PI-2620
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
45 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)

NCT06289582
View directory record Official record
Conditions
Parkinson Disease
Interventions
[F-18]DPA714 administration IV
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cholinergic Nicotinic Receptors and Cognition in PD

NCT02076295
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 9, 2026, 1:50 AM EDT
Completed Phase 1 Interventional

Improve Speech Using an In-the-ear Device in Parkinson's Disease

NCT00488657
View directory record Official record
Conditions
Parkinson's Disease, Dysarthria
Interventions
SpeechEasy Model ITC
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2013 · Synced Oct 9, 2026, 1:50 AM EDT
Not listed No phase listed Observational

Measures of Mitochondria Dysfunction in PD

NCT04300608
View directory record Official record
Conditions
Parkinson Disease, Mitochondrial
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
65 Years to 85 Years
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 9, 2026, 1:50 AM EDT
Not listed Not applicable Interventional

Augmenting Treatment Effects of Voice Therapy in Parkinson Disease

NCT02265315
View directory record Official record
Conditions
Parkinson Disease
Interventions
Transcranial Magnetic Stimulation, Lee Silverman Voice Treatment
Other · Behavioral
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
45 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational

Long Term Follow Up KET-PD

NCT06164756
View directory record Official record
Conditions
Parkinson's Disease, Depression
Interventions
Cognitive Behavior Therapy (CBT), Treatment As Usual (TAU)
Other
Lead sponsor
Yale University
Other
Eligibility
40 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting Phase 2 Interventional

A Comparative Performance Study Between High and Standard Resolution Positron Emission Tomography Camera Using [18F] AV-133 in Prodromal Parkinson's Disease

NCT07809438
View directory record Official record
Conditions
Prodromal Parkinson's Disease
Interventions
[18F] AV-133 PET Imaging
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Active, not recruiting Not applicable Interventional

Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

NCT04675398
View directory record Official record
Conditions
Parkinson Disease
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fox BioNet Project: ECV-003

NCT03775447
View directory record Official record
Conditions
Parkinson Disease
Interventions
Lumbar Puncture
Procedure
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Chicago, Illinois • Portland, Oregon • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electromyography Signals as Biomarkers for Parkinson's Disease

NCT02168504
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Norconnect Inc
Industry
Eligibility
25 Years to 82 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Ogdensburg, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting No phase listed Observational

Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

NCT07642908
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
45 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Completed No phase listed Observational

The GBA Multimodal Study in Parkinson's Disease

NCT04101968
View directory record Official record
Conditions
Parkinson Disease, GBA Gene Mutation, Gaucher Disease
Interventions
PET scan, neuroQWERTY
Diagnostic Test
Lead sponsor
Pacific Parkinson's Research Centre
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 9, 2026, 1:50 AM EDT
Recruiting Phase 2 Interventional

Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

NCT07265596
View directory record Official record
Conditions
Prodromal Parkinsons Disease
Interventions
[18F] AV-133 PET Imaging
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 9, 2026, 1:50 AM EDT
Completed Not applicable Interventional Results available

Prism Adaptation Treatment of Parkinson's Disease

NCT02380859
View directory record Official record
Conditions
Parkinson
Interventions
Prism adaptation
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
40 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Oct 9, 2026, 1:50 AM EDT