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ClinicalTrials.gov public records Last synced Oct 1, 2026, 7:24 PM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Orthopaedic Research Foundation Clear all
Recruiting Phase 3 Interventional Accepts healthy volunteers

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

NCT03295981
View directory record Official record
Conditions
Giant Cell Tumor of Bone
Interventions
Zoledronic Acid
Drug
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
14
States / cities
Los Angeles, California • Indianapolis, Indiana • Iowa City, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Autologous Chondrocyte Implantation in the Patellofemoral Joint

NCT00212849
View directory record Official record
Conditions
Chondrosis, Patellar Articular Cartilage Lesions, Trochlear Articular Cartilage Lesions
Interventions
Not listed
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
18 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2005
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 21, 2005 · Synced Oct 1, 2026, 7:24 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

CBD Knee Scope Study

NCT05934500
View directory record Official record
Conditions
Post-operative Pain
Interventions
Cannabidiol Oil
Drug
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Retro/Prospective Multi-Centre Data Capture on REDAPT Sleeved Stem

NCT05600712
View directory record Official record
Conditions
Safety and Performance
Interventions
REDAPT Sleeved Stem
Device
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 1, 2026, 7:24 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Prospective Trial of the TriFit™ Web Knee Brace

NCT03633071
View directory record Official record
Conditions
Satisfaction
Interventions
Web-knee brace
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting Not applicable Interventional

ARVIS TKA vs Conventional TKA

NCT06663384
View directory record Official record
Conditions
Osteoarthritis
Interventions
Evaluation of Augmented Reality technology in TKA compared to standard TKA
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Not applicable Interventional Results available

Early Postoperative Compex Rehab NMES Use for Total Knee Arthroplasty Patients

NCT01844193
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Compex Rehab
Device
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
45 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Greenwood, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison of INSORB Staples With Metal Staples in Total Hip Replacement

NCT00940446
View directory record Official record
Conditions
Erythema, Drainage, Bruising, Pain
Interventions
Insorb staples, metal staples (Ethicon metal stapler)
Device
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 1, 2026, 7:24 PM EDT
Completed No phase listed Observational

The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)

NCT01825161
View directory record Official record
Conditions
Secondary Malignant Neoplasm of Vertebral Column
Interventions
Not listed
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
18 Years to 75 Years
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
5
States / cities
Kansas City, Kansas • Baltimore, Maryland • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Not applicable Interventional Results available

Energy Dispersive Bracing for Conservative Treatment of Knee Osteoarthritis

NCT02388646
View directory record Official record
Conditions
Knee Osteoarthritis, Arthritis
Interventions
Exercise Only, Brace Only, Bracing + Exercises
Other · Device
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
21 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Greenwood, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 1, 2026, 7:24 PM EDT
Completed No phase listed Observational

MRI Evaluation of Integrity Implant for Rotator Cuff Tears

NCT06353893
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Anika Integrity Implant System
Device
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Proximal Humerus Fractures: A Retrospective Analysis

NCT03637608
View directory record Official record
Conditions
Proximal Humeral Fracture
Interventions
Not listed
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting Phase 4 Interventional

Post-op Prednisone and Glucose Monitoring in TKA

NCT07630896
View directory record Official record
Conditions
Osteoarthritis, Unicompartmental Knee Arthroplasty, Total Hip Arthroplasty (THA)
Interventions
Prednisone, Continuous Glucose Monitor, InkWell Health Tattoos
Drug · Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Not applicable Interventional Results available

The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery

NCT02767427
View directory record Official record
Conditions
Infection, Spinal Injuries
Interventions
Chlorhexidine Wipes, No intervention
Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2023 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effectiveness of Splinting After Collagenase Injection

NCT04874870
View directory record Official record
Conditions
Dupuytren Contracture, Dupuytren's Disease
Interventions
Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis
Drug · Combination Product
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 1, 2026, 7:24 PM EDT
Not listed No phase listed Observational

Elbow Arthroscopy Data Analysis

NCT03656185
View directory record Official record
Conditions
Osteoarthritis Elbow Left, Osteoarthritis Elbow Right, Lateral Epicondylitis, Left Elbow, Lateral Epicondylitis, Right Elbow, Plica Syndromes, Osteochondritis Dissecans
Interventions
Not listed
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Timeline
2018 – 2024
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting Not applicable Interventional

Woodcasting Versus Thermoplast Splint in CMC Arthroplasty

NCT06876350
View directory record Official record
Conditions
Carpometacarpal (CMC) Joint Arthritis
Interventions
Woodcasting Splint, Control (Standard treatment)
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting Not applicable Interventional

Accelerated Flap Coverage in Severe Lower Extremity Trauma

NCT06293469
View directory record Official record
Conditions
Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
Interventions
Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
356 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
7
States / cities
Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting No phase listed Observational

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

NCT06883396
View directory record Official record
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Retrospective Analysis on Distal Humerus Fractures

NCT03637621
View directory record Official record
Conditions
Distal Humerus Fracture
Interventions
ORIF
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 1, 2026, 7:24 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Posterior Approach to Total Shoulder Arthroplasty

NCT03623269
View directory record Official record
Conditions
Total Shoulder Arthroplasty, Osteo Arthritis Shoulders
Interventions
posterior approach to total shoulder arthroplasty
Procedure
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Oct 1, 2026, 7:24 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effectiveness of Cannabidiol vs. Narcotics for Post Operative Pain Control in Elective Shoulder Arthroscopic Surgery

NCT05240755
View directory record Official record
Conditions
Post-operative Pain
Interventions
Cannabidiol Oil
Drug
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Oct 1, 2026, 7:24 PM EDT
Recruiting Not applicable Interventional

Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?

NCT07552415
View directory record Official record
Conditions
Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Interventions
Knee immobilizer, No Knee Immobilizer
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 1, 2026, 7:24 PM EDT
Suspended Early Phase 1 Interventional Accepts healthy volunteers

Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome

NCT03722303
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Fat Injection, Steroid Injection
Other · Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 1, 2026, 7:24 PM EDT