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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:13 PM EDT

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Showing 1–24 of 127 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Parkinson's Foundation Clear all
Not listed No phase listed Observational

Measures of Mitochondria Dysfunction in PD

NCT04300608
View directory record Official record
Conditions
Parkinson Disease, Mitochondrial
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
65 Years to 85 Years
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 6, 2026, 10:13 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Food Effect Study of BMS-984923 in Healthy Older Adult Volunteers

NCT05817643
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
BMS-984923
Drug
Lead sponsor
Allyx Therapeutics
Industry
Eligibility
50 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Phase 2 Interventional Results available

Effects of Cholinergic Augmentation on Measures of Balance and Gait

NCT02206620
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Donepezil
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 14, 2019 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Not applicable Interventional

A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease

NCT01646333
View directory record Official record
Conditions
Parkinson's Disease, Mild Cognitive Impairment
Interventions
Memory and Problem-Solving Intervention, Supportive Therapy
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Not applicable Interventional

Impact of Exercise in Parkinson's Disease

NCT03495193
View directory record Official record
Conditions
Parkinson Disease
Interventions
Exercise training, Sleep hygiene
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 6, 2026, 10:13 PM EDT
Not listed Not applicable Interventional

Augmenting Treatment Effects of Voice Therapy in Parkinson Disease

NCT02265315
View directory record Official record
Conditions
Parkinson Disease
Interventions
Transcranial Magnetic Stimulation, Lee Silverman Voice Treatment
Other · Behavioral
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
45 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 6, 2026, 10:13 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

NCT07020026
View directory record Official record
Conditions
Parkinson's Disease
Interventions
[18F]PI-2620
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
45 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 6, 2026, 10:13 PM EDT
Completed No phase listed Observational

PROGENI (Parkinson's Research: The Organized Genetics Initiative) Family Study of LRRK2 (Leucine-rich Repeat Kinase 2)

NCT01536821
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
9
States / cities
Weston, Florida • Indianapolis, Indiana • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Food-Drug Interaction Study of Serum Urate After Oral Inosine

NCT02614469
View directory record Official record
Conditions
Healthy
Interventions
Inosine
Drug
Lead sponsor
Michael Alan Schwarzschild
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Evansville, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 6, 2026, 10:13 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Neuroimaging of Parkinson's

NCT07024875
View directory record Official record
Conditions
Parkinsons Disease (PD)
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

rTMS for Motor and Mood Symptoms of Parkinson's Disease

NCT01080794
View directory record Official record
Conditions
Parkinson's Disease, Depression
Interventions
Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
5
States / cities
Los Angeles, California • Gainesville, Florida • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Phase 1 Interventional

Improve Speech Using an In-the-ear Device in Parkinson's Disease

NCT00488657
View directory record Official record
Conditions
Parkinson's Disease, Dysarthria
Interventions
SpeechEasy Model ITC
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2013 · Synced Oct 6, 2026, 10:13 PM EDT
Recruiting Not applicable Interventional

Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease

NCT06602544
View directory record Official record
Conditions
Parkinson Disease (PD)
Interventions
Robotic Apparel
Device
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Allston, Massachusetts • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 6, 2026, 10:13 PM EDT
Active, not recruiting No phase listed Observational

Genotypic Influences on Network Progression in Parkinson's Disease

NCT04228172
View directory record Official record
Conditions
Parkinson's Disease
Interventions
DNA/GeneticTesting, FDG PET scan, MRI scan, Clinical and neuropsychological assessments
Genetic · Radiation · Other
Lead sponsor
Northwell Health
Other
Eligibility
40 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 6, 2026, 10:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Systemic Synuclein Sampling Study (S4)

NCT02572713
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Biofluid samplings, Tissue samplings, DaTSCAN™
Procedure · Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Birmingham, Alabama • Scottsdale, Arizona • New Haven, Connecticut + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Not applicable Interventional

Singing in Groups for Parkinson's Disease; A Pilot Study of Group Singing Therapy for PD-related Voice/Speech Impairment

NCT01163331
View directory record Official record
Conditions
Voice Quality and Voice Loudness Associated With Parkinson's Disease
Interventions
Singing Therapy
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Phase 2 Interventional Results available

Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease

NCT00909545
View directory record Official record
Conditions
Parkinson Disease
Interventions
Isradipine CR 5mg, Isradipine CR 10mg, Isradipine CR 20mg, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
18
States / cities
Sunnyvale, California • New Haven, Connecticut • Jacksonville, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2013 · Synced Oct 6, 2026, 10:13 PM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

NCT03713957
View directory record Official record
Conditions
Parkinson Disease
Interventions
GRF6021, Placebo
Drug · Other
Lead sponsor
Alkahest, Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Englewood, Colorado • Doral, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 6, 2026, 10:13 PM EDT
Recruiting Phase 2 Interventional

A Comparative Performance Study Between High and Standard Resolution Positron Emission Tomography Camera Using [18F] AV-133 in Prodromal Parkinson's Disease

NCT07809438
View directory record Official record
Conditions
Prodromal Parkinson's Disease
Interventions
[18F] AV-133 PET Imaging
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 6, 2026, 10:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cholinergic Nicotinic Receptors and Cognition in PD

NCT02076295
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 6, 2026, 10:13 PM EDT
Terminated Not applicable Interventional

Cycling in Parkinson's Disease

NCT02175082
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Cycling at Forced rate, Cycling at self-selected rate
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
30 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 6, 2026, 10:13 PM EDT
Terminated Phase 1 Interventional

A Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AVE8112 in Patients With Parkinson's Disease

NCT01803945
View directory record Official record
Conditions
Parkinson's Disease
Interventions
AVE8112, Placebo
Drug
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
35 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Glendale, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2015 · Synced Oct 6, 2026, 10:13 PM EDT
Terminated Phase 2 Interventional

A Phase 2 Study to Evaluate the Safety and Efficacy of RM-131 in Patients With Parkinson's Disease & Chronic Constipation

NCT01955616
View directory record Official record
Conditions
Parkinson's Disease
Interventions
RM-131, Placebo
Drug
Lead sponsor
Motus Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
13
States / cities
Los Angeles, California • Englewood, Colorado • Gainesville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2016 · Synced Oct 6, 2026, 10:13 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

NCT04477785
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
30 Years and older
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2033
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 6, 2026, 10:13 PM EDT