Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 13, 2026, 1:14 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.

Filters: Sponsor: Prisma Health-Midlands Clear all

Conditions: Migraine in Adolescence, Headache, Mood Disturbance
Interventions: Apollo Neuro; Device
Lead sponsor: University of South Carolina; Other
Eligibility: 10 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Osteoarthritis, Knee, Osteoarthritis Knees Both, Joint Inflammation
Interventions: Astaxanthin, Placebo; Drug · Other
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 99 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication, Narcotic Intoxication
Interventions: Flumazenil, Naloxone; Drug
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Pregnancy Related, Sedentary Behavior
Interventions: NEAT!2 sedentary behavior app, Pregnancy smartphone app; Behavioral · Other
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older · Female only
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Knee Arthroplasty
Interventions: Standard Physical Therapy, Physical therapist discuss aerobic physical activity, Physical activity session; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 40 Years to 79 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Columbia, South Carolina

Conditions: Osteoarthritis, Knee
Interventions: Zero Degree Knee Positioner; Device
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 40 Years to 80 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Tissue Plasminogen Activator
Interventions: early tPA and DNase; Combination Product
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Closed Fracture of Shaft of Humerus
Interventions: Not listed
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 7
States / cities: Indianapolis, Indiana • Boston, Massachusetts • Burlington, Massachusetts + 4 more

Conditions: Acute Respiratory Distress Syndrome
Interventions: N-acetyl cysteine; Drug
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Doula Support, Postpartum, Postpartum Depression (PPD), Postpartum Anemia
Interventions: Doula-delivered, Nurse-coordinated postpartum support; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older · Female only
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor, DICER1 Syndrome, Cystic Nephroma, Wilms Tumor, Pineoblastoma, Renal Sarcoma, Nodular Hyperplasia of Thyroid, Nasal Chondromesenchymal Hamartoma, Ciliary Body Medulloepithelioma, Neuroblastoma, Pituitary Cancer, Embryonal Rhabdomyosarcoma, Ovarian Sarcoma, Gynandroblastoma, Thyroid Carcinoma, Embryonal Rhabdomyosarcoma of Vagina (Diagnosis), Embryonal Rhabdomyosarcoma of Uterus (Diagnosis), Embryonal Rhabdomyosarcoma of Cervix, Intracranial Sarcoma
Interventions: Not listed
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 0 Minutes to 100 Years
Enrollment: 3,400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2036
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Atrial Fibrillation
Interventions: No AAD post Ablation.; Other
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Plantar Fascitis
Interventions: HP Arize 3D-Printed Orthotics, Traditional Orthotics; Device
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 100 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Lexington, South Carolina

Conditions: Post Operative Patients
Interventions: Food Related Visual Stimuli Exposure; Behavioral
Lead sponsor: Casey Morehouse, DO; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Ankle Arthrodesis, MTP Arthrodesis
Interventions: Vitamin D3; Drug
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 99 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 2
States / cities: Charleston, South Carolina • Columbia, South Carolina

Conditions: Neoplasms, Breast
Interventions: Physical Therapy; Other
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Hypertensive Disorder
Interventions: Blood pressure cuff; Device
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years to 54 Years · Female only
Enrollment: 421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Cardiac Arrest
Interventions: Echocardiography, Electrocardiogram (ECG); Diagnostic Test
Lead sponsor: Romolo Gaspari; Other
Eligibility: 18 Years and older
Enrollment: 813 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 6
States / cities: Hartford, Connecticut • Lebanon, New Hampshire • Stony Brook, New York + 3 more

Conditions: Blood Pressure Monitoring, Hypertension (HTN), Pregnancy
Interventions: Enhanced Care Group, Remote Blood Pressure Monitoring alone; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older · Female only
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Bunion of Unspecified Foot, Bunionette of Unspecified Foot, Hammertoe, Ankle Fractures, Achilles Tendon Surgery
Interventions: Acetominophen, Toradol, Meloxicam, Cyclobenzaprine, Lyrica; Drug
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 99 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Carcinoma, Squamous Cell, Cancer of the Head and Neck
Interventions: Hyperbaric Oxygen Therapy, Hyperbaric oxygen; Drug
Lead sponsor: National Baromedical Services; Other
Eligibility: 18 Years to 70 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 3
States / cities: Rochester, Minnesota • Lebanon, New Hampshire • Norfolk, Virginia

Conditions: Diabetes Mellitus, Diabetic Peripheral Neuropathy, Diabetic Foot Ulcer
Interventions: Lovaza, L-Arginine Powder, Vitamin C; Drug
Lead sponsor: Prisma Health-Midlands; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Preterm Birth, Blood Transfusion Complication, Hypothermia
Interventions: Ranger blood warmer (3M Healthcare, Oakdale, Minnesota); Device
Lead sponsor: University of South Carolina; Other
Eligibility: 24 Weeks to 32 Weeks
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Concussion, Brain
Interventions: Apollo Neuro; Device
Lead sponsor: University of South Carolina; Other
Eligibility: 10 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Columbia, South Carolina

Search by objective public record fields.

A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents

Astaxanthin for Management of Inflammation in Knee Osteoarthritis

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

An mHealth Intervention for Sedentary Behavior in Pregnant Women

The PATH Study to Promote Physical Activity After Knee Replacement

Zero Degree Knee Positioner for Improved Earley Knee Extension Following Total Knee Arthroplasty

Early Intrapleural TPA Instillation Versus Late

Operative Versus Nonoperative Treatment of Humeral Shaft Fractures: A Prospective Cohort Comparison Study

N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome

The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.

International PPB/DICER1 Registry

Comparison of Recurrence of Atrial Fibrillation Post Cryoballon Ablation During the 90-day Blanking Period-with and Without Anti-arrhythmic Drug Therapy

HP Arize 3D Orthotics for Planar Fasciitis

The Food Network Effect

Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery

Early Rehabilitation for Breast Cancer - A Randomized Control Trial

Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women

Vfib by ECG or Echo During Cardiac Arrest

Community Health Worker Coaching to Reduce Cardiovascular Risk Among Women After a Hypertensive Disorder of Pregnancy

Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study

Dose Escalation Study of Hyperbaric Oxygen With Radiation and Chemotherapy to Treat Squamous Cell Carcinoma of the Head and Neck

Immunonutrition for Diabetic Foot Ulcers

Blood Warming in Preterm Infants to Decrease Hypothermia

A Wrist-Worn Nerve Stimulator for Remediating Persistent Post-Concussive Symptoms in Adolescents