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ClinicalTrials.gov public records Last synced Oct 27, 2026, 6:53 AM EDT

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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Sharp HealthCare Clear all
Not listed Not applicable Interventional

PREMOD2 With Near Infrared Spectroscopy Sub-study

NCT03145142
View directory record Official record
Conditions
Hypoxia, Brain, Premature Birth
Interventions
Umbilical cord milking, Delayed Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 27, 2026, 6:53 AM EDT
Recruiting No phase listed Observational

Cool Prime Comparative Effectiveness Study for Mild HIE

NCT04621279
View directory record Official record
Conditions
Mild Hypoxic Ischemic Encephalopathy of Newborn
Interventions
Normothermia, Whole body therapeutic hypothermia
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
36 Weeks and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 27, 2026, 6:53 AM EDT
Not yet recruiting Not applicable Interventional

Parent Perceptions of OptiPAP Junior

NCT07837700
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD), Preterm Birth Complication, Pulmonary, CPAP
Interventions
Nasal CPAP interface: OptiPAP Junior, Nasal CPAP interface: FlexiTrunk
Device
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 30 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 27, 2026, 6:53 AM EDT
Completed No phase listed Observational

The Neu-Prem Trial: Neuromonitoring of Preterm Newborn Brain During Birth Resuscitation

NCT02605733
View directory record Official record
Conditions
Neurologic Manifestations, Premature Birth, Hypoxia-Ischemia, Brain
Interventions
EEG, NIRS
Device
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 72 Hours
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 27, 2026, 6:53 AM EDT
Terminated No phase listed Observational Results available

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

NCT04518228
View directory record Official record
Conditions
HIV, Tuberculosis
Interventions
Bictegravir (BIC), Tenofovir alafenamide (TAF), Long-acting injectable formulation of cabotegravir (CAB LA), Dolutegravir (DTG), Atazanavir/ritonavir (ATV/r), Darunavir/ritonavir (DRV/r), Lopinavir/ritonavir (LPV/r), Cobicistat, Ritonavir, First-Line TB Treatment, Second-Line TB Treatment, Doravirine (DOR)
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
13
States / cities
Los Angeles, California • San Diego, California • Aurora, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Echocardiography Sub-Study of the Umbilical Cord Milking in Non-Vigorous Infants Trial (MINVI)

NCT03798093
View directory record Official record
Conditions
Birth Asphyxia
Interventions
Umbilical Cord Milking, Early Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
35 Weeks to 42 Weeks
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
Completed No phase listed Observational

Changes in Cardiac Output During Delayed Umbilical Cord Clamping

NCT02195037
View directory record Official record
Conditions
Cardiac Output, Low
Interventions
Not listed
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 1 Minute
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Core Warming in COVID-19 Patients Undergoing Mechanical Ventilation

NCT04494867
View directory record Official record
Conditions
Covid19
Interventions
Core Warming, Standard of Care
Device · Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Oct 27, 2026, 6:53 AM EDT
Not yet recruiting Not applicable Interventional

Rapid Diagnostics for Genetic Disorders in Neonates

NCT07005700
View directory record Official record
Conditions
Acid Base Disorder
Interventions
Targeted genomic sequencing
Diagnostic Test
Lead sponsor
Sharp HealthCare
Other
Eligibility
1 Day to 6 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Time to Accurate Heart Rate on Neonatal Outcomes

NCT04587934
View directory record Official record
Conditions
Premature Infant, Extremely Low Birth Weight, Extreme Prematurity
Interventions
iRes Warmer with ResusView, iRes Warmer without ResusView
Device · Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 32 Weeks
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Oct 27, 2026, 6:53 AM EDT
Not yet recruiting Phase 3 Interventional

NICU Antibiotics and Outcomes (NANO) Follow-up Study

NCT05977400
View directory record Official record
Conditions
Premature Birth, Antibiotics, Neurodevelopment
Interventions
Ampicillin, Gentamicin, Placebo
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
14
States / cities
San Diego, California • New Haven, Connecticut • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Umbilical Cord Milking in Non-Vigorous Infants Developmental Followup (MINVIFU)

NCT03621943
View directory record Official record
Conditions
Neurodevelopmental Abnormality
Interventions
Umbilical Cord Milking, Early Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
22 Months to 26 Months
Enrollment
1,207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
7
States / cities
Davis, California • Loma Linda, California • San Diego, California + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
No Longer Available No phase listed Expanded access

A Single Patient IND for PD-0325901

NCT02297802
View directory record Official record
Conditions
Prior Treatment With PD-0325901 With Ongoing Clinical Response
Interventions
PD-0325901
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2014 · Synced Oct 27, 2026, 6:53 AM EDT
Completed No phase listed Observational

Detection of Atelectasis or Pneumothorax and Resolution With Electrical Impedance Tomography (EIT) in Newborn Infants

NCT04848727
View directory record Official record
Conditions
Atelectasis Neonatal, Pneumothorax and Air Leak
Interventions
Detecting asymmetric lung disease like atelectasis or pneumothorax with electrical impedance tomography (EIT)
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 27, 2026, 6:53 AM EDT
Not listed Not applicable Interventional

Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)

NCT03476980
View directory record Official record
Conditions
Neurodevelopmental Abnormality
Interventions
Randomized to Umbilical Cord Milking at birth, Randomized to Delayed Cord Clamping at birth
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
22 Months to 42 Months
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
15
States / cities
Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 27, 2026, 6:53 AM EDT
Withdrawn No phase listed Observational

Use of Antibiotic Carrier in Acute Periprosthetic Infections (APPI) of Total Knee Replacements

NCT02107924
View directory record Official record
Conditions
Infection
Interventions
APPI of TKR-Stimulan
Procedure
Lead sponsor
Michael Muldoon, M.D.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 26, 2014 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Neonatal Resuscitation With Intact Cord

NCT02231411
View directory record Official record
Conditions
Intraventricular Hemorrhage
Interventions
V-DCC, Delayed cord clamping, Dry and and if apneic initially can stimulate by gently rubbing the back for approximately 30 seconds with warm sterile towels
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 31 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 27, 2026, 6:53 AM EDT
Completed No phase listed Observational

Validation of Fore-Sight Cerebral & Tissue Oximeter Saturation Measurements on Neonates ≤ 5 kg

NCT02017652
View directory record Official record
Conditions
Bowel Motility
Interventions
Not listed
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 7 Days
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants

NCT04209946
View directory record Official record
Conditions
Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
Interventions
Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
24 Weeks to 29 Weeks
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Irvine, California • Loma Linda, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Trigger Finger Orthotic Wearing Schedules

NCT04094389
View directory record Official record
Conditions
Trigger Finger
Interventions
Orthotic continuous wear group, Orthotic wear during waking hours only group, Orthotic wear only while sleeping group
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated May 15, 2020 · Synced Oct 27, 2026, 6:53 AM EDT
Not listed Phase 4 Interventional

IVIG in Patients With Severe COVID-19 Requiring Mechanical Ventilation

NCT04616001
View directory record Official record
Conditions
Covid19, SARS-CoV Infection
Interventions
IVIG
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer

NCT01540994
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
Radiation Therapy
Radiation
Lead sponsor
Sharp HealthCare
Other
Eligibility
50 Years to 90 Years · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
Recruiting No phase listed Observational

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

NCT00404989
View directory record Official record
Conditions
HIV Infections, Hepatitis B
Interventions
Not listed
Lead sponsor
Syneos Health
Other
Eligibility
12 Years to 60 Years · Female only
Enrollment
24,258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1989 – 2099
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 27, 2026, 6:53 AM EDT
Completed Phase 4 Interventional Results available

Do Angiotensin Receptor Blockers Mitigate Progression to Acute Respiratory Distress Syndrome With SARS-CoV-2 Infection

NCT04340557
View directory record Official record
Conditions
SARS-CoV Infection
Interventions
Losartan
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Oct 27, 2026, 6:53 AM EDT