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Showing 1–24 of 1,105 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: The Cleveland Clinic Clear all
Completed Phase 4 Interventional

Rapydan Topical Anaesthesia for Arterial Cannulation

NCT01494311
View directory record Official record
Conditions
Arterial Catheterization
Interventions
Lidocaine/tetracaine patch, Placebo Patch, Subcutaneous injection of 0.5 ml Lidocain 1%, Subcutaneous injection of saline
Drug
Lead sponsor
Medical University of Vienna
Other
Eligibility
18 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Phase 3 Interventional

The Effects of Hypercapnia, Supplemental Oxygen, and Dexamethasone on Surgical Wound Infection

NCT00273377
View directory record Official record
Conditions
Surgical Wound Infection, Surgery, Colon
Interventions
Mild intraoperative hypercapnia (50 mmHg vs. 30 mmHg), Supplemental oxygen (80% vs. 30%), Dexamethasone, Placebo
Other · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
2
States / cities
Louisville, Kentucky • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Jul 23, 2026, 8:14 PM EDT
Terminated No phase listed Observational

PeriOperative Bridging - Perioperative Anticoagulation in the Setting of Recent Intracoronary Drug Eluting Stents

NCT00606151
View directory record Official record
Conditions
Stent Thrombosis
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2009 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

The Effects of Dual Task Training in Individuals With Parkinson's Disease

NCT02538029
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Dual Task Group, Single Task Group
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Jul 23, 2026, 8:14 PM EDT
Recruiting Not applicable Interventional

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

NCT03870672
View directory record Official record
Conditions
Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach, Sham rTMS approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 23, 2026, 8:14 PM EDT
Terminated Not applicable Interventional

Intraoperative Anesthesia Care Transition Checklist

NCT02453828
View directory record Official record
Conditions
Postoperative Complications
Interventions
Non-cardiac surgery
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
7,348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Jul 23, 2026, 8:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

COVID-19 and Obstetric Transmission

NCT04418557
View directory record Official record
Conditions
COVID, Pregnancy Complications
Interventions
RT-PCR and antibody testing
Diagnostic Test
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Jul 23, 2026, 8:14 PM EDT
Recruiting Not applicable Interventional

Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

NCT04096014
View directory record Official record
Conditions
Hepatic Encephalopathy
Interventions
Ensure Enlive, Standard Of Care
Dietary Supplement · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Phase 4 Interventional Results available

Transition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2D

NCT04538352
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Semaglutide, Insulin Degludec, Insulin aspart
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Knee Pain on Walking Biomechanics

NCT05670236
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Lidocaine Hydrochloride
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
45 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Not applicable Interventional

A Pilot Study Swiftsure

NCT05578599
View directory record Official record
Conditions
Ventilated Patients
Interventions
Swiftsure CCS device
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Jul 23, 2026, 8:14 PM EDT
No Longer Available No phase listed Expanded access

Use Of 3,4-Diaminopyridine (3,4-DAP) In The Treatment Of Lambert Eaton Myasthenic Syndrome

NCT01373333
View directory record Official record
Conditions
Lambert-Eaton Myasthenic Syndrome
Interventions
3,4 DAP
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1997
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Jul 23, 2026, 8:14 PM EDT
Completed No phase listed Observational

Lacrimal Drainage Resistance Study

NCT01766232
View directory record Official record
Conditions
Epiphora, Nasolacrimal Duct Obstruction, Canalicular Stenosis, Functional Tear Pump Failure, Ectropion
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Jul 23, 2026, 8:14 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

HA35 Acute Alcohol Study

NCT05025865
View directory record Official record
Conditions
Healthy Controls
Interventions
Sodium Hyaluronate, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed No phase listed Observational

Diagnosing Respiratory Disease in Children Using Cough Sounds 2

NCT03392363
View directory record Official record
Conditions
Pneumonia, Bronchiolitis, Asthma Exacerbation, Croup, Reactive Airway Disease, Upper Respiratory Disease, Viral Lower Respiratory Tract Infections, Lower Respiratory Disease
Interventions
Recordings of Infants and Children's Cough Sounds
Device
Lead sponsor
ResApp Health Limited
Industry
Eligibility
29 Days to 12 Years
Enrollment
1,470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Boston, Massachusetts • Cleveland, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Jul 23, 2026, 8:14 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180)

NCT03702816
View directory record Official record
Conditions
Alzheimer Disease, Parkinson Disease, Inflammation
Interventions
GE180 PET Scan
Drug
Lead sponsor
Aaron Ritter, MD
Other
Eligibility
55 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 23, 2026, 8:14 PM EDT
Terminated Phase 4 Interventional Results available

CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes

NCT02912455
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
canagliflozin, Placebo (for canagliflozin)
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Adherence in Pediatric Multiple Sclerosis

NCT02234713
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Motivational Interview, Video Attention Control
Behavioral · Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
10 Years to 18 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
11
States / cities
Birmingham, Alabama • Loma Linda, California • San Francisco, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Multiscore Feedback in Professionalism for Anesthesia

NCT01522560
View directory record Official record
Conditions
CA2 and CA3 Residents Doing a Two Month Rotation in, Pediatric Anesthesia Department
Interventions
Feedback group, Control group
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Improving SCI Rehabilitation Interventions by Retraining the Brain

NCT03892746
View directory record Official record
Conditions
Cervical Spinal Cord Injruy
Interventions
Active tDCS + task oriented practice, Sham tDCS + task oriented practice
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
4
States / cities
West Orange, New Jersey • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PIONEER: Intraoperative and Perioperative OCT Study

NCT02423161
View directory record Official record
Conditions
Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Jul 23, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Portable Monitoring for Diagnosis and Management of Sleep Apnea

NCT00642486
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG)
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

NCT04748861
View directory record Official record
Conditions
High Intensity Exercise, Normal Cognition, Exercise Intervention
Interventions
Indoor Cycling (IC)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
65 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jul 23, 2026, 8:14 PM EDT
Completed No phase listed Observational

Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma

NCT02897128
View directory record Official record
Conditions
Sarcoma, Soft Tissue
Interventions
Observational Only - Transcutaneous Oxygen Measurement
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Gainesville, Florida • Iowa City, Iowa • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Jul 23, 2026, 8:14 PM EDT