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ClinicalTrials.gov public records Last synced Oct 7, 2026, 4:10 AM EDT

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Showing 1–24 of 86 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: The Hospital for Sick Children Clear all
Active, not recruiting Phase 3 Interventional

Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial

NCT04333823
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Dapagliflozin 5mg, Placebo
Drug
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
12 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

NCT04604418
View directory record Official record
Conditions
Congenital Heart Disease in Children
Interventions
No intervention. It is observational
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Effects of Anorexia Nervosa on Bone Mass in Adolescents

NCT00088153
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Physiologic Estrogen/progesterone, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting Not applicable Interventional

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

NCT06232304
View directory record Official record
Conditions
Systemic Lupus Erythematosus of Childhood (Disorder)
Interventions
TEACH
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
12 Years to 22 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Grand Rapids, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

SPRINT: Signature for Pain Recovery IN Teens

NCT04285112
View directory record Official record
Conditions
Pain, Chronic, Pain, Joint Pain, Musculoskeletal Pain
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
11 Years to 18 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
2
States / cities
Palo Alto, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting Phase 2 Interventional

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

NCT06358638
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Daratumumab, Alemtuzumab, Sirolimus, Total Body Irradiation
Drug · Radiation
Lead sponsor
Children's National Research Institute
Other
Eligibility
2 Years to 25 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2054
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Optimizing Nutrition and Milk (Opti-NuM) Project

NCT06870981
View directory record Official record
Conditions
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification, Human Milk Microbiome, Human Milk Feeding, Human Milk Nutrition, Growth &Amp; Development
Interventions
Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
1 Hour to 21 Days
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
2
States / cities
Palo Alto, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting Not applicable Interventional

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

NCT05219110
View directory record Official record
Conditions
Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection, Hemolytic-Uremic Syndrome
Interventions
Infusion of 200% maintenance fluids as balanced crystalloid IV solution, Oral fluids; infusion of up to 110% maintenance fluids as balanced crystalloid IV solution
Other
Lead sponsor
University of Calgary
Other
Eligibility
9 Months to 21 Years
Enrollment
1,040 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
22
States / cities
Birmingham, Alabama • Little Rock, Arkansas • La Jolla, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Not applicable Interventional Results available

Intervention to Improve Adherence in Teen Kidney Transplant

NCT01356277
View directory record Official record
Conditions
Kidney Transplantation, Medication Adherence
Interventions
Action-focused problem-solving, Electronic pillbox monitoring, dose reminders, and feedback
Behavioral · Device
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
11 Years to 24 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
St Louis, Missouri • Cincinnati, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 7, 2026, 4:10 AM EDT
Not listed Phase 2 Interventional

Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

NCT02840409
View directory record Official record
Conditions
Low Grade Glioma
Interventions
Vinblastine, Bevacizumab
Drug
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
6 Months to 18 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Aurora, Colorado • Washington D.C., District of Columbia + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Coaching Language to Improve Endoscopy Training Quality

NCT05674500
View directory record Official record
Conditions
Education, Medical, Colonoscopy
Interventions
Educational Training on standardized coaching language, Educational Training on goal setting
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Oct 7, 2026, 4:10 AM EDT
Terminated Phase 1Phase 2 Interventional

Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers

NCT02992964
View directory record Official record
Conditions
Refractory or Recurrent Hypermutated Malignancies, Biallelic Mismatch Repair Deficiency (bMMRD) Positive Patients
Interventions
Nivolumab
Drug
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
12 Months to 18 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 7, 2026, 4:10 AM EDT
Active, not recruiting Not applicable Interventional

ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer

NCT05792566
View directory record Official record
Conditions
Pediatric Cancer
Interventions
Atomic app
Other
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
10 Years to 30 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

IIPE-PRIS Accelerating Safe Signouts

NCT02403466
View directory record Official record
Conditions
Serious Medical Errors, Resident Sign-out
Interventions
Resident Handoff Bundle
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
875 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
9
States / cities
Palo Alto, California • San Francisco, California • Bethesda, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 7, 2026, 4:10 AM EDT
Terminated Phase 1Phase 2 Interventional

Tamoxifen Therapy for Myotubular Myopathy

NCT04915846
View directory record Official record
Conditions
X Linked Myotubular Myopathy
Interventions
ApoTamox 10mg, Placebo
Drug
Lead sponsor
James Dowling
Other
Eligibility
6 Months and older · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 7, 2026, 4:10 AM EDT
Active, not recruiting Not applicable Interventional

Prophylactic Antibiotics or Placebo After Hypospadias Repair

NCT02096159
View directory record Official record
Conditions
Hypospadias
Interventions
trimethoprim-sulfamethoxazole, placebo
Drug · Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 5 Years · Male only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

NCT04629014
View directory record Official record
Conditions
Pediatric Intestinal Failure
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Months to 25 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
11
States / cities
Birmingham, Alabama • Aurora, Colorado • Hartford, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Not applicable Interventional

Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus

NCT04335643
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
TEACH
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
12 Years to 22 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Completed No phase listed Observational

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

NCT04702243
View directory record Official record
Conditions
Primary Ciliary Dyskinesia, Primary Immune Deficiency, Kartagener Syndrome
Interventions
Genetic Testing for PCD or PID, Unaffected Family Member Genetic Testing
Diagnostic Test · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
5 Years to 45 Years
Enrollment
436 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
6
States / cities
Palo Alto, California • Aurora, Colorado • Bethesda, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Not listed Not applicable Interventional

FIT-ATOMIC Exercise Feasibility Trial

NCT06870968
View directory record Official record
Conditions
Neuroinflammatory Diseases, Multiple Sclerosis
Interventions
Exercise Training, Mobility and Flexibility Training
Behavioral
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
11 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
La Jolla, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 7, 2026, 4:10 AM EDT
Completed Not applicable Interventional

Virtual Parental Presence on Induction

NCT04574219
View directory record Official record
Conditions
Anxiety, Surgery
Interventions
Use of Facetime with child and parents during induction
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
4 Years to 12 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting No phase listed Observational

Osteochondritis Dissecans of Knee Prospective Cohort

NCT02771496
View directory record Official record
Conditions
Osteochondritis Dissecans
Interventions
Other: observational only- no intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2074
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 7, 2026, 4:10 AM EDT
Terminated Phase 1 Interventional Results available

Thrombolysis in Pediatric Stroke (TIPS)

NCT01591096
View directory record Official record
Conditions
Stroke
Interventions
Tissue plasminogen activator (Activase®)
Drug
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
2 Years to 17 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
13
States / cities
Palo Alto, California • Aurora, Colorado • Boston, Massachusetts + 9 more
Source: ClinicalTrials.gov public record
Updated May 25, 2018 · Synced Oct 7, 2026, 4:10 AM EDT
Recruiting Not applicable Interventional

iCanCope With Post-Operative Pain (iCanCope PostOp)

NCT05382962
View directory record Official record
Conditions
Pain, Chronic, Pain, Chronic Post-Surgical
Interventions
iCanCope Post Op Application
Behavioral
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
12 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 7, 2026, 4:10 AM EDT