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Completed Phase 3 Interventional

Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx

ClinicalTrials.gov ID: NCT00002496

Public ClinicalTrials.gov record NCT00002496. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 17, 2026, 8:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

PHASE III TRIAL TO PRESERVE THE LARYNX: INDUCTION CHEMOTHERAPY AND RADIATION THERAPY VERSUS CONCOMITANT CHEMOTHERAPY AND RADIATION THERAPY VERSUS RADIATION THERAPY

Study identification

NCT ID
NCT00002496
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Radiation Therapy Oncology Group
Network
Enrollment
Not listed

Conditions and interventions

Interventions

  • chemotherapy Drug
  • cisplatin Drug
  • conventional surgery Procedure
  • fluorouracil Drug
  • low-LET cobalt-60 gamma ray therapy Radiation
  • low-LET electron therapy Radiation
  • low-LET photon therapy Radiation

Drug · Procedure · Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 1992
Primary completion
Jul 31, 2002
Completion
Oct 31, 2013
Last update posted
Jan 23, 2014

1992 – 2013

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
CCOP - Colorado Cancer Research Program, Inc. Denver Colorado 80209-5031
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612
Veterans Affairs Medical Center - Atlanta (Decatur) Decatur Georgia 30033
CCOP - Illinois Oncology Research Association Peoria Illinois 61602
CCOP - Carle Cancer Center Urbana Illinois 61801
Indiana University Cancer Center Indianapolis Indiana 46202-5265
Veterans Affairs Medical Center - Indianapolis (Roudebush) Indianapolis Indiana 46202
CCOP - Iowa Oncology Research Association Des Moines Iowa 50309-1016
New England Medical Center Hospital Boston Massachusetts 02111
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
CCOP - Kalamazoo Kalamazoo Michigan 49007-3731
CCOP - Metro-Minnesota Saint Louis Park Minnesota 55416
Veterans Affairs Medical Center - East Orange East Orange New Jersey 07018-1095
CCOP - Northern New Jersey Hackensack New Jersey 07601
Ireland Cancer Center Cleveland Ohio 44106-5065
Hahnemann University Hospital Philadelphia Pennsylvania 19102-1192
University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002496, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 23, 2014 · Synced May 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00002496 live on ClinicalTrials.gov.

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