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Completed Phase 2 Interventional

Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00005850

Public ClinicalTrials.gov record NCT00005850. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 7:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Fluoxetine in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC): A Phase II Pilot Study to Improve Quality of Life During Chemotherapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This trial is designed to test the efficacy of fluoxetine to improve patient's quality of life during chemotherapy. An innovative application of a selective serotonin reuptake inhibitor may modulate the effects of fatigue, anxiety and depression which worsen quality of life.

Study identification

NCT ID
NCT00005850
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
21 participants

Conditions and interventions

Eligibility (public fields only)

Age range
Not listed
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2001 (Type not available)
Primary completion
Sep 2003 (Actual)
Completion
Sep 2003 (Actual)
Last update posted
Jul 4, 2016

2001 – 2003

United States locations

U.S. sites
42
U.S. states
21
U.S. cities
38
Facility City State ZIP Site status
Northeast Alabama Regional Medical Center Anniston Alabama 36207 —
Veterans Affairs Medical Center - San Diego San Diego California 92161 —
Veterans Affairs Medical Center - Washington, DC Washington D.C. District of Columbia 20422 —
Broward General Medical Center Fort Lauderdale Florida 33316 —
Memorial Regional Hospital Comprehensive Cancer Center Hollywood Florida 33021 —
Florida Hospital Cancer Institute Orlando Florida 32804 —
Helen and Harry Gray Cancer Institute at Good Samaritan Medical Center West Palm Beach Florida 33401 —
University of Chicago Cancer Research Center Chicago Illinois 60637-1470 —
Louis A. Weiss Memorial Hospital Chicago Illinois 60640 —
West Suburban Center for Cancer Care River Forest Illinois 60305 —
Saint Anthony Medical Center Rockford Illinois 61108 —
Fort Wayne Medical Oncology and Hematology, Incorporated Fort Wayne Indiana 46885-5099 —
Baptist Hospital East - Louisville Louisville Kentucky 40207 —
Veterans Affairs Medical Center - Baltimore Baltimore Maryland 21201 —
Massachusetts General Hospital Cancer Center Boston Massachusetts 02114 —
Beth Israel Medical Center Boston Massachusetts 02115 —
Lakeland Medical Center - St. Joseph Saint Joseph Michigan 49085 —
Ellis Fischel Cancer Center - Columbia Columbia Missouri 65203 —
Barnes-Jewish Hospital St Louis Missouri 63110 —
University of Nebraska Medical Center Omaha Nebraska 68198-7680 —
Veterans Affairs Medical Center - Las Vegas Las Vegas Nevada 89106 —
Cooper University Hospital Camden New Jersey 08103 —
Elmhurst Hospital Center Elmhurst New York 11373 —
Queens Cancer Center of Queens Hospital Jamaica New York 11432 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
State University of New York - Upstate Medical University Syracuse New York 13210 —
Veterans Affairs Medical Center - Syracuse Syracuse New York 13210 —
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. Syracuse New York 13217 —
Veterans Affairs Medical Center - Asheville Asheville North Carolina 28805 —
NorthEast Oncology Associates Concord North Carolina 28025 —
Veterans Affairs Medical Center - Durham Durham North Carolina 27705 —
Cape Fear Valley Health System Fayetteville North Carolina 28302-2000 —
Lenoir Memorial Hospital Cancer Center Kinston North Carolina 28503-1678 —
FirstHealth Moore Regional Hospital Pinehurst North Carolina 28374 —
New Hanover Regional Medical Center Wilmington North Carolina 28402-9025 —
Veterans Affairs Medical Center - Fargo Fargo North Dakota 58102 —
Veterans Affairs Medical Center - Dallas Dallas Texas 75216 —
Martha Jefferson Hospital Charlottesville Virginia 22901 —
Virginia Oncology Associates - Norfolk Norfolk Virginia 23502 —
Oncology and Hematology Associates of Southwest Virginia, Inc. Roanoke Virginia 24014 —
St. Mary's Medical Center Huntington West Virginia 25701 —
Ministry Medical Group - Northern Region Rhinelander Wisconsin 54501 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00005850, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 4, 2016 · Synced Nov 6, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00005850 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →