Sequenced Treatment Alternatives to Relieve Depression (STAR*D)
Public ClinicalTrials.gov record NCT00021528. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Sequenced Treatment Alternatives to Relieve Depression
Study identification
- NCT ID
- NCT00021528
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- National Institute of Mental Health (NIMH)
- NIH
- Enrollment
- 4,000 participants
Conditions and interventions
Conditions
Interventions
- BuproprionSR Drug
- Cognitive Therapy Behavioral
- Lithium Drug
- T3 (Triiodothyronine) Drug
- VenlafaxineXR Drug
- buspirone Drug
- citalopram Drug
- mirtazapine Drug
- nortriptyline Drug
- sertraline Drug
- tranylcypromine Drug
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2001
- Primary completion
- Not listed
- Completion
- Aug 31, 2006
- Last update posted
- Sep 24, 2009
2001 – 2006
United States locations
- U.S. sites
- 41
- U.S. states
- 13
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham VA Medical Center | Birmingham | Alabama | 35223 | — |
| Tuscaloosa VA Mental Health Clinic - Veterans Only | Tuscaloosa | Alabama | 35404 | — |
| Tuscaloosa VA Primary Care Center | Tuscaloosa | Alabama | 35404 | — |
| Psychiatric Centers at San Diego | Chula Vista | California | 91910 | — |
| Harbor UCLA Family Health Care Center | Harbor City | California | 90710 | — |
| UCLA General Outpatient Psychiatry Clinic | Los Angeles | California | 90024 | — |
| UCLA Internal Medicine Clinic | Los Angeles | California | 90024 | — |
| UCSD Outpatient Psychiatric Services | San Diego | California | 92103 | — |
| Veterans Affairs Medical Center/FIRM Primary Care Clinic | San Diego | California | 92161 | — |
| Harbor UCLA Medical Center | Torrance | California | 90509 | — |
| Northwestern Outpatient Treatment Care Center | Chicago | Illinois | 60611 | — |
| University of Illinois at Chicago Clinic | Chicago | Illinois | 60612 | — |
| Evanston Outpatient Clinic | Evanston | Illinois | 60201 | — |
| COMCARE of Sedgwick County | Wichita | Kansas | 67203 | — |
| Psychiatric Outpatient Clinic | Wichita | Kansas | 67214-2878 | — |
| Swampscott Family Doctors | Boston | Massachusetts | 01907 | — |
| Internal Medicine Associates | Boston | Massachusetts | 02114 | — |
| MGH/Charlestown Clinic | Charlestown | Massachusetts | 02129 | — |
| MGH/Salem Professional | Salem | Massachusetts | 01970 | — |
| General Psychiatric Ambulatory Clinic | Ann Arbor | Michigan | 48105-0722 | — |
| Briarwood Family Practice Clinic | Ann Arbor | Michigan | 48109-0708 | — |
| LIJ/Zucker Hillside Adult Ambulatory Care Center | Glen Oaks | New York | 11004 | — |
| LIJ North Shore Medical Group | Lake Success | New York | 11040 | — |
| UNC Chapel Hill General Medicine Clinic | Chapel Hill | North Carolina | 27599-7110 | — |
| UNC Chapel Hill Adult Diagnostic & Treatment Clinic | Chapel Hill | North Carolina | 27599-7160 | — |
| UNC Chapel Hill Family Practice Clinic | Chapel Hill | North Carolina | 27955 | — |
| Springer Family Medicine | Tulsa | Oklahoma | 74135 | — |
| Laureate Psychiatric Clinic & Hospital | Tulsa | Oklahoma | 74136 | — |
| Warren Clinic | Tulsa | Oklahoma | 74136 | — |
| Diversified Human Services Clinic | Pittsburgh | Pennsylvania | 15062 | — |
| Latterman Family Health Center | Pittsburgh | Pennsylvania | 15132 | — |
| Bellefield Clinic of WPIC | Pittsburgh | Pennsylvania | 15213 | — |
| AMPN Corkery, Heise & Dainesi | Upper Saint Clair | Pennsylvania | 15317 | — |
| Psychiatric Consultants, P.C. | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center-Mental Health Center | Nashville | Tennessee | 37212 | — |
| Vine Hill Community Clinic | Nashville | Tennessee | 37212 | — |
| Centerstone/Luton Mental Health Services | Nashville | Tennessee | 37217 | — |
| The Holiner Psychiatric Group | Dallas | Texas | 75230 | — |
| UT Southwestern Family Medicine Clinic | Dallas | Texas | 75390 | — |
| MCV Primary Care Clinic | Richmond | Virginia | 23220 | — |
| MCV Family Counseling | Richmond | Virginia | 23298-0268 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00021528, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2009 · Synced May 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00021528 live on ClinicalTrials.gov.