Combination Chemotherapy and Radiation in Treating Patients With Stage III or IV Head and Neck Cancer (Paradigm Trial)

ClinicalTrials.gov ID: NCT00095875

Public ClinicalTrials.gov record NCT00095875. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Jun 25, 2026, 9:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase III Comparing Sequential Therapy With TPF/Chemoradiation (ST) To Cisplatinum-Based Chemoradiotherapy [PARADIGM TRIAL]

Study identification

NCT ID: NCT00095875
Recruitment status: Completed
Study type: Interventional
Phase: Phase 3
Lead sponsor: Dana-Farber Cancer Institute; Other
Enrollment: 145 participants

Conditions and interventions

Conditions

Head and Neck Cancer

Interventions

carboplatin Drug
cisplatin Drug
docetaxel Drug
fluorouracil Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 31, 2004
Primary completion: Mar 31, 2012
Completion: Mar 31, 2012
Last update posted: Nov 18, 2013

2004 – 2012

United States locations

U.S. sites: 14
U.S. states: 14
U.S. cities: 14

Facility	City	State	ZIP	Site status
Rebecca and John Moores UCSD Cancer Center	La Jolla	California	92093-0658	—
CCOP - Colorado Cancer Research Program	Denver	Colorado	80224	—
Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus	Boca Raton	Florida	33486	—
Winship Cancer Institute of Emory University	Atlanta	Georgia	30322	—
Cardinal Bernardin Cancer Center at Loyola University Medical Center	Maywood	Illinois	60153	—
Maine Center for Cancer Medicine and Blood Disorders - Scarborough	Scarborough	Maine	04074	—
Greenebaum Cancer Center at University of Maryland Medical Center	Baltimore	Maryland	21201	—
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute	Boston	Massachusetts	02115	—
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis	St Louis	Missouri	63110	—
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center	Lebanon	New Hampshire	03756-0002	—
UMDNJ University Hospital	Newark	New Jersey	07103	—
Albert Einstein Cancer Center at Albert Einstein College of Medicine	The Bronx	New York	10461	—
Blumenthal Cancer Center at Carolinas Medical Center	Charlotte	North Carolina	28232-2861	—
UPMC Cancer Centers	Pittsburgh	Pennsylvania	15232	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00095875, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 18, 2013 · Synced Jun 25, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00095875 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →