Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Terminated Phase 2 Interventional Results available

Efficacy and Safety of LBH589B in Adult Patients With Multiple Myeloma

ClinicalTrials.gov ID: NCT00445068

Public ClinicalTrials.gov record NCT00445068. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 12:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Study Of Oral LBH589 In Adult Patients With Multiple Myeloma Who Have Received At Least Two Prior Lines Of Therapy And Whose Disease Is Refractory To The Most Recent Line Of Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the efficacy and safety of LBH589B in adult patients with multiple myeloma who have received at least two prior therapies and are refractory to their last therapy. Patients must have received in prior therapy either bortezomib or lenalidomide

Study identification

NCT ID
NCT00445068
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
38 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 16, 2007 (Actual)
Primary completion
May 19, 2008 (Actual)
Completion
Dec 25, 2009 (Actual)
Last update posted
Jul 14, 2021

2007 – 2009

United States locations

U.S. sites
24
U.S. states
17
U.S. cities
22
Facility City State ZIP Site status
Mayo Clinic Scottsdale Arizona 85259 —
Aptium Oncology Berkeley California 94704 —
City of Hope Duarte California 91010 —
UCSF San Francisco California 94143 —
Stanford Stanford California 94305 —
Rocky Mountain Cancer Center Denver Colorado 80218 —
Christiana Care Newark Delaware 19718 —
Moffitt Cancer Center Tampa Florida 33612 —
Emory University Atlanta Georgia 30322 —
Rush University Chicago Illinois 60612 —
University of Chicago Chicago Illinois 60637 —
Indiana University Indianapolis Indiana 46203 —
University of Iowa Iowa City Iowa 52240-1515 —
Dana Farber Boston Massachusetts 02115 —
University of Michigan Ann Arbor Michigan 48109 —
Washington University St Louis Missouri 63110 —
Hackensack University Hackensack New Jersey 07456 —
Duke Durham North Carolina 27710 —
Wake Forest Winston-Salem North Carolina 27157 —
Metrohealth Cleveland Ohio 44109 —
Sarah Canon Research Center Nashville Tennessee 37203 —
Vanderbilt Nashville Tennessee 37212 —
University of Texas Southwestern Dallas Texas 75390-9179 —
CTRC San Antonio Texas 78258 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00445068, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 14, 2021 · Synced Oct 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00445068 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →