An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets
Public ClinicalTrials.gov record NCT00643851. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Multicenter, Randomized, Double-Blind, Active Controlled, Parallel Group, Phase 3 Trial to Evaluate the Safety and Efficacy of Dapagliflozin in Combination With Metformin as Initial Therapy as Compared With Dapagliflozin Monotherapy and Metformin Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical research study is to learn if initiating treatment with BMS-51248 (Dapagliflozin) in combination with metformin XR can improve diabetes control in patients with Type 2 Diabetes who do not receive any pharmacological treatment for diabetes, when compared to initial treatment with monotherapy dapagliflozin or metformin XR. The safety of this treatment will also be studied
Study identification
- NCT ID
- NCT00643851
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 994 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 77 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2008 (Type not available)
- Primary completion
- Aug 2009 (Actual)
- Completion
- Aug 2009 (Actual)
- Last update posted
- Jan 30, 2023
2008 – 2009
United States locations
- U.S. sites
- 44
- U.S. states
- 18
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Greystone Medical Research, Llc | Birmingham | Alabama | 35242 | — |
| Winston Technology Research, Llc | Haleyville | Alabama | 35565 | — |
| Clinical Research Advantage, Inc. | Tempe | Arizona | 85282 | — |
| John Muir Physician Network Clinical Research Center | Concord | California | 94520 | — |
| Southland Clinical Research Center, Inc. | Fountain Valley | California | 92708 | — |
| Valley Research | Fresno | California | 93720 | — |
| Central Florida Clinical Trials, Inc. | Altamonte Springs | Florida | 32701 | — |
| Clinical Therapeutics Corporation | Coral Gables | Florida | 33134 | — |
| Florida Research Network, Llc | Gainesville | Florida | 32605 | — |
| Fpa Clinical Research | Kissimmee | Florida | 34741 | — |
| Nextphase Clinical Trials, Inc. | Miami | Florida | 33145 | — |
| Middle Georgia Drug Study Center, Llc | Perry | Georgia | 31069 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607 | — |
| Deerbrook Medical Associates | Vernon Hills | Illinois | 60061 | — |
| Jackson Clinic | Rolling Fork | Mississippi | 39159 | — |
| Mercy Medical Group/Dba Woodlake Research | Chesterfield | Missouri | 63017 | — |
| Hudson Valley Clinical Research Center | Kingston | New York | 12401 | — |
| Metrolina Medical Research | Charlotte | North Carolina | 28209 | — |
| Crescent Medical Research | Salisbury | North Carolina | 28144 | — |
| Community Health Care, Inc. | Canal Fulton | Ohio | 44614 | — |
| Wells Institute For Health Awareness | Kettering | Ohio | 45429 | — |
| Newark Physician Associates | Newark | Ohio | 43055 | — |
| Physician Research, Inc. | Zanesville | Ohio | 43701 | — |
| Gilbert Medical Research, Llc | Bethany | Oklahoma | 73008 | — |
| Integris Family Care South Penn | Oklahoma City | Oklahoma | 73159 | — |
| Integris Family Care Yukon | Yukon | Oklahoma | 73099 | — |
| Willamette Valley Clinical Studies | Eugene | Oregon | 97404 | — |
| Commonwealth Primary Care, Pc / Fleetwood Clinical Research | Fleetwood | Pennsylvania | 19522 | — |
| Biomedical Research Associates, Llc | Shippensburg | Pennsylvania | 17257 | — |
| Safe Harbor Clinical Research | East Providence | Rhode Island | 02914 | — |
| Southeastern Research Associates, Inc. | Greenville | South Carolina | 29605 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Middle Tennessee Clinical Research | Fayetteville | Tennessee | 37334 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Endocrine Associates | Houston | Texas | 77004 | — |
| Village Family Practice | Houston | Texas | 77024 | — |
| Non-Invasive Cardiovascular, Pa | Houston | Texas | 77074 | — |
| Excel Clinical Research, Llc | Houston | Texas | 77081 | — |
| Texas Center For Drug Development | Houston | Texas | 77081 | — |
| Inst. Of Clin. Research At The Diabetes Cntr. Of The Sw | Midland | Texas | 79705 | — |
| Hill Country Medical Associates | New Braunfels | Texas | 78130 | — |
| Southwest Clinical Research Center, Llc | Pearland | Texas | 77584 | — |
| Covenant Clinical Research, Pa | San Antonio | Texas | 78229 | — |
| S.A.M. Clinical Research Center | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00643851, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 30, 2023 · Synced Nov 4, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00643851 live on ClinicalTrials.gov.