Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Subjects That Are Taking Saxagliptin Added Onto Metformin XR Compared to Subjects Taking Metformin XR Alone

ClinicalTrials.gov ID: NCT00683657

Public ClinicalTrials.gov record NCT00683657. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 10:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 4-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial To Evaluate The Efficacy And Safety Of Saxagliptin In Comparison To Placebo As Add On Treatment To Metformin XR In Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control With Diet And Exercise And A Stable Dose Of Metformin ≥1500 mg/Day

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This protocol will compare 24 hour glucose control for subject taking saxagliptin and metformin extended release (XR) versus metformin XR alone

Study identification

NCT ID
NCT00683657
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
93 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 77 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2008
Primary completion
Jan 31, 2009
Completion
Jan 31, 2009
Last update posted
May 31, 2015

2008 – 2009

United States locations

U.S. sites
13
U.S. states
8
U.S. cities
13
Facility City State ZIP Site status
Dedicated Phase I, Inc. Phoenix Arizona 85013
Amcr Institute, Inc Escondido California 92026
Irvine Center For Clinical Research, Inc. Irvine California 92618
Pacific Sleep Medicine Services (Avastra Clinical Trials) Redlands California 92373
Advantage Clinical Research Santa Ana California 92701
Orange County Research Center Tustin California 92780
River Birch Research Alliance, Llc Blue Ridge Georgia 30513
Endocrine Research Solutions, Inc. Roswell Georgia 30076
Jasper Clinic, Inc. Kalamazoo Michigan 49007
Clinilabs, Inc. New York New York 10019
Covance Cru, Inc. Portland Oregon 97239
Dgd Research, Inc. San Antonio Texas 78229
Avastra Clinical Trials Midvale Utah 84047

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

Recently updated Type 2 Diabetes trials

Other public records listing Type 2 Diabetes. Sorted by last update posted; newest first. Not a recommendation.

All Type 2 Diabetes trials →

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00683657, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 31, 2015 · Synced Sep 3, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00683657 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →