- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
- Interventions
- BioPoly, surgical standard of care (SSOC)
- Device · Procedure
- Lead sponsor
- BioPoly LLC
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Fort Wayne, Indiana • Indianapolis, Indiana • Rochester, Minnesota + 1 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 28
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Articular Cartilage Defects in the Knee Joint
- Interventions
- GelrinC, Microfracture historical control arm
- Device · Other
- Lead sponsor
- Regentis Biomaterials
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 13
- States / cities
- La Mesa, California • Orange, California • Denver, Colorado + 10 more
- Conditions
- Femoroacetabular Impingement, Chondral Lesions
- Interventions
- Platelet-rich plasma (PRP), Saline
- Biological · Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Chondral Defect, Osteochondritis Dissecans (OCD), Articular Cartilage Defect, Articular Cartilage Disorder of Knee
- Interventions
- MACI, microfracture
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 12
- States / cities
- Palo Alto, California • Sacramento, California • New Orleans, Louisiana + 7 more
- Conditions
- Insufficiency Fractures, Stress Fracture, Stress Fracture, Ankle, Foot and Toes
- Interventions
- Treatment of insufficiency fractures
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 11
- States / cities
- Mesa, Arizona • Sun City, Arizona • Capitola, California + 8 more
- Conditions
- Osteochondral Lesion of Talus
- Interventions
- Microfracture with Bone Marrow Aspirate Concentrate, Microfracture
- Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Defect of Articular Cartilage
- Interventions
- Hyalofast, Microfracture
- Device · Procedure
- Lead sponsor
- Anika Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2026
- U.S. locations
- 18
- States / cities
- Tempe, Arizona • Los Angeles, California • San Diego, California + 14 more
- Conditions
- Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
- Interventions
- Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
- Biological · Other
- Lead sponsor
- ISTO Technologies, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
- Conditions
- Cartilage Loss, Microfracture
- Interventions
- Unloader Bracing, Non-Bracing
- Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 15 Years to 40 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Redwood City, California
- Conditions
- Knee Injuries, Joint Surface Knee Lesions
- Interventions
- Marketed Product - MP01, Surgical Standard of Care
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- La Mesa, California
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Cartilage or Osteochondral Defects in the Knee, Up to Moderate Osteoarthritis
- Interventions
- Agili-C implant, SSOC
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 251 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 11
- States / cities
- San Diego, California • New Orleans, Louisiana • Salisbury, Maryland + 7 more
- Conditions
- Articular Cartilage of the Femoral Condyle Between 2-6cm2
- Interventions
- Microfracture, NOVOCART 3D
- Procedure · Biological
- Lead sponsor
- Aesculap Biologics, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 233 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2027
- U.S. locations
- 30
- States / cities
- La Mesa, California • Los Angeles, California • Redwood City, California + 26 more
- Conditions
- Degenerative Lesion of Articular Cartilage of Knee
- Interventions
- Episealer Knee System, Microfracture
- Device · Procedure
- Lead sponsor
- Episurf Medical Inc.
- Industry
- Eligibility
- 30 Years to 70 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 8
- States / cities
- Tempe, Arizona • La Mesa, California • New Orleans, Louisiana + 5 more
- Conditions
- Bone Marrow Edema
- Interventions
- Subchondroplasty
- Procedure
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2021
- U.S. locations
- 6
- States / cities
- Encinitas, California • New Lenox, Illinois • New York, New York + 3 more
- Conditions
- Articular Cartilage Injury
- Interventions
- Kensey Nash Corp. Cartilage Repair Device, Microfracture
- Device · Procedure
- Lead sponsor
- Kensey Nash Corporation
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 2
- States / cities
- Salisbury, Maryland • Kirkwood, Missouri
- Conditions
- Degenerative Lesion of Articular Cartilage of Knee
- Interventions
- ADSC Application, Microfracture
- Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 3
- States / cities
- Redwood City, California • Santa Monica, California • Denver, Colorado
- Conditions
- Articular Cartilage Damage
- Interventions
- NeoCart, microfracture
- Biological · Procedure
- Lead sponsor
- Histogenics Corporation
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2014
- U.S. locations
- 6
- States / cities
- San Francisco, California • Bloomington, Minnesota • New York, New York + 3 more
- Conditions
- Articular Cartilage Defects in the Knee Joint
- Interventions
- NeoCart, Microfracture
- Biological · Procedure
- Lead sponsor
- Histogenics Corporation
- Industry
- Eligibility
- 18 Years to 59 Years
- Enrollment
- 245 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 29
- States / cities
- Tucson, Arizona • La Mesa, California • Orange, California + 26 more
- Conditions
- Outcomes of Allograft
- Interventions
- Not listed
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Defect of Articular Cartilage, Osteochondritis Dissecans
- Interventions
- Microfracture, Cartilage Autograft Implantation System
- Procedure · Device
- Lead sponsor
- DePuy Mitek
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 27
- States / cities
- Tucson, Arizona • Bentonville, Arkansas • Encinitas, California + 24 more
- Conditions
- Chondral Defect, Articular Cartilage Defect
- Interventions
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 17 Years to 65 Years
- Enrollment
- 309 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 7
- States / cities
- Sacramento, California • Washington D.C., District of Columbia • Wichita, Kansas + 4 more
- Conditions
- Articular Cartilage Defect Grade III or IV of the Knee
- Interventions
- Autologous Cell, Standard microfracture arthroscopic surgery
- Procedure
- Lead sponsor
- Fondren Orthopedic Group L.L.P.
- Other
- Eligibility
- 18 Years to 68 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Osteochondral Lesions of Talus
- Interventions
- ankle arthroscopy with debridement and microfracture of the OLT, Bone Marrow Aspirate injection
- Procedure · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina