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Completed Phase 2Phase 3 Interventional Results available

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

ClinicalTrials.gov ID: NCT01061736

Public ClinicalTrials.gov record NCT01061736. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 11:20 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Multicenter, Two-part, Dose Ranging and Confirmatory Study With an Operationally Seamless Design, Evaluating Efficacy and Safety of SAR153191 on Top of Methotrexate (MTX) in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to MTX Therapy

Study identification

NCT ID
NCT01061736
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Sanofi
Industry
Enrollment
1,675 participants

Conditions and interventions

Interventions

  • Sarilumab Drug
  • Placebo (for sarilumab) Drug
  • Methotrexate Drug
  • Folic Acid Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2010
Primary completion
Sep 30, 2013
Completion
Sep 30, 2013
Last update posted
Jun 27, 2017

2010 – 2013

United States locations

U.S. sites
45
U.S. states
20
U.S. cities
42
Facility City State ZIP Site status
Investigational Site Number 840070 Anniston Alabama 36207
Investigational Site Number 840004 Birmingham Alabama 35205
Investigational Site Number 840072 Gilbert Arizona 85234
Investigational Site Number 840029 Beverly Hills California 90211
Investigational Site Number 840007 Palm Desert California 92260
Investigational Site Number 840008 San Francisco California 94143
Investigational Site Number 840021 Santa Maria California 94354
Investigational Site Number 840049 Upland California 91786
Investigational Site Number 840050 Dunedin Florida 34698
Investigational Site Number 840041 Jacksonville Florida 32209
Investigational Site Number 840067 Jupiter Florida 33458
Investigational Site Number 840048 Miami Florida 33155
Investigational Site Number 840006 Orlando Florida 32806
Investigational Site Number 840063 Palm Harbor Florida 34684
Investigational Site Number 840060 Sarasota Florida 34239
Investigational Site Number 840003 Atlanta Georgia 30322
Investigational Site Number 840028 Decatur Georgia 30033
Investigational Site Number 840027 Marietta Georgia 30060
Investigational Site Number 840018 Idaho Falls Idaho 83404
Investigational Site Number 840046 Chicago Illinois 60612
Investigational Site Number 840015 Lexington Kentucky 40504
Investigational Site Number 840073 Cumberland Maryland 21502
Investigational Site Number 840055 Frederick Maryland 21702
Investigational Site Number 840013 Wheaton Maryland 20902
Investigational Site Number 840066 St Louis Missouri 63117
Investigational Site Number 840071 Omaha Nebraska 68114
Investigational Site Number 840056 New York New York 10016
Investigational Site Number 840068 Hickory North Carolina 28601
Investigational Site Number 840044 Toledo Ohio 43606
Investigational Site Number 840002 Oklahoma City Oklahoma 73103
Investigational Site Number 840011 Tulsa Oklahoma 74104
Investigational Site Number 840065 Tulsa Oklahoma 74135
Investigational Site Number 840010 Bethlehem Pennsylvania 18015
Investigational Site Number 840009 Duncansville Pennsylvania 16635
Investigational Site Number 840062 Reading Pennsylvania 19611
Investigational Site Number 840058 Columbia South Carolina 29204
Investigational Site Number 840016 North Charleston South Carolina 29406
Investigational Site Number 840025 Jackson Tennessee 38305
Investigational Site Number 840001 Dallas Texas 75231
Investigational Site Number 840022 Dallas Texas 75235
Investigational Site Number 840012 Dallas Texas 75390
Investigational Site Number 840020 Houston Texas 77034
Investigational Site Number 840069 Lubbock Texas 79424
Investigational Site Number 840074 Mesquite Texas 75150
Investigational Site Number 840061 Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 217 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01061736, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 27, 2017 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01061736 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →