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Completed Phase 3 Interventional Results available

A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease

ClinicalTrials.gov ID: NCT01224106

Public ClinicalTrials.gov record NCT01224106. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 2:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Two Year Study to Evaluate the Effect of Subcutaneous RO4909832 on Cognition and Function in Prodromal Alzheimer's Disease With Option for up to an Additional Two Years of Treatment and an Open-Label Extension With Active Study Treatment

Study identification

NCT ID
NCT01224106
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
799 participants

Conditions and interventions

Interventions

  • Gantenerumab Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 29, 2010
Primary completion
Sep 9, 2020
Completion
Sep 9, 2020
Last update posted
Dec 12, 2021

2010 – 2020

United States locations

U.S. sites
24
U.S. states
16
U.S. cities
24
Facility City State ZIP Site status
Banner Alzheimer's Institute Phoenix Arizona 85006
University of California, San Diego La Jolla California 92037
Yale University ADRU New Haven Connecticut 06510
Brain Matters Research, Inc. Delray Beach Florida 33445
Infinity Clinical Research Hollywood Florida 33024
Accelerated Enrollment Solutions Orlando Florida 32806
Roskamp Institute, Inc. Sarasota Florida 34243
Compass Research The Villages Florida 32162
Premiere Research Institute West Palm Beach Florida 33407
Indiana University Indianapolis Indiana 46202
Boston Center for Memory Newton Massachusetts 02459
Western Michigan University Homer Stryker M.D. School of Medicine Center for Clinical Research Kalamazoo Michigan 49008
Neurological Research Center Hattiesburg Mississippi 39401
Princeton Medical Institute Princeton New Jersey 08540
Nathan Kline Institute Orangeburg New York 10962
University of Rochester Medical Center; Monroe Community Hospital Rochester New York 14627
Alzheimer's Memory Center Matthews North Carolina 28105
Oregon Health and Science University, Layton Aging and Alzheimer's Disease Center Portland Oregon 97239
Northeastern Pennsylvania Memory Plains Pennsylvania 18705
Rhode Island Mood & Memory Research Institute East Providence Rhode Island 02914
Butler Hospital Providence Rhode Island 02906
Senior Adults Specialty Research Austin Texas 78757
Texas Neurology PA Dallas Texas 75206
Clinical Neuroscience Research Associates, Inc. Bennington Vermont 05201

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 115 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01224106, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 12, 2021 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01224106 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →