A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial
Public ClinicalTrials.gov record NCT01727726. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo and Active Comparator Controlled Trial of Flexible-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare the efficacy of brexpiprazole (flexible dose) with placebo as adjunctive therapy to an assigned open label antidepressant therapy (ADT) in the proposed subject population with MDD.
Study identification
- NCT ID
- NCT01727726
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,182 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2012 (Type not available)
- Primary completion
- Oct 17, 2016 (Actual)
- Completion
- Nov 10, 2016 (Actual)
- Last update posted
- Jun 8, 2018
2012 – 2016
United States locations
- U.S. sites
- 44
- U.S. states
- 20
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Bellflower | California | — | — |
| Not listed | Beverly Hills | California | — | — |
| Not listed | Costa Mesa | California | 92626 | — |
| Not listed | Glendale | California | — | — |
| Not listed | Irvine | California | — | — |
| Not listed | Redlands | California | — | — |
| Not listed | San Diego | California | — | — |
| Not listed | Upland | California | — | — |
| Not listed | Gainesville | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jacksonville Beach | Florida | — | — |
| Not listed | Leesburg | Florida | — | — |
| Not listed | Melbourne | Florida | — | — |
| Not listed | Miami | Florida | 33015 | — |
| Not listed | Miami | Florida | 33145 | — |
| Not listed | Oakland Park | Florida | — | — |
| Not listed | Orange City | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Decatur | Georgia | — | — |
| Not listed | Lake Charles | Louisiana | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Belmont | Massachusetts | — | — |
| Not listed | Roslindale | Massachusetts | — | — |
| Not listed | Watertown | Massachusetts | 02472 | — |
| Not listed | Creve Coeur | Missouri | — | — |
| Not listed | Lebanon | New Hampshire | — | — |
| Not listed | New York | New York | 10003 | — |
| Not listed | New York | New York | 10168 | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Dayton | Ohio | — | — |
| Not listed | Edmond | Oklahoma | 73013 | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Salem | Oregon | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Murray | Utah | — | — |
| Not listed | Herndon | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Bellevue | Washington | — | — |
| Not listed | Kirkland | Washington | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Brown Deer | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01727726, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 8, 2018 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01727726 live on ClinicalTrials.gov.