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Completed Phase 3 Interventional Results available

A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial

ClinicalTrials.gov ID: NCT01727726

Public ClinicalTrials.gov record NCT01727726. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 10:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind, Placebo and Active Comparator Controlled Trial of Flexible-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial

Study identification

NCT ID
NCT01727726
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Enrollment
2,182 participants

Conditions and interventions

Interventions

  • Brexpiprazole Drug
  • Seroquel XR Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2012
Primary completion
Oct 16, 2016
Completion
Nov 9, 2016
Last update posted
Jun 7, 2018

2012 – 2016

United States locations

U.S. sites
44
U.S. states
20
U.S. cities
42
Facility City State ZIP Site status
Not listed Birmingham Alabama
Not listed Phoenix Arizona
Not listed Little Rock Arkansas
Not listed Bellflower California
Not listed Beverly Hills California
Not listed Costa Mesa California 92626
Not listed Glendale California
Not listed Irvine California
Not listed Redlands California
Not listed San Diego California
Not listed Upland California
Not listed Gainesville Florida
Not listed Jacksonville Florida
Not listed Jacksonville Beach Florida
Not listed Leesburg Florida
Not listed Melbourne Florida
Not listed Miami Florida 33015
Not listed Miami Florida 33145
Not listed Oakland Park Florida
Not listed Orange City Florida
Not listed Orlando Florida
Not listed Decatur Georgia
Not listed Lake Charles Louisiana
Not listed Baltimore Maryland
Not listed Belmont Massachusetts
Not listed Roslindale Massachusetts
Not listed Watertown Massachusetts 02472
Not listed Creve Coeur Missouri
Not listed Lebanon New Hampshire
Not listed New York New York 10003
Not listed New York New York 10168
Not listed Columbus Ohio
Not listed Dayton Ohio
Not listed Edmond Oklahoma 73013
Not listed Portland Oregon
Not listed Salem Oregon
Not listed Dallas Texas
Not listed Murray Utah
Not listed Herndon Virginia
Not listed Richmond Virginia
Not listed Bellevue Washington
Not listed Kirkland Washington
Not listed Seattle Washington
Not listed Brown Deer Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01727726, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 7, 2018 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01727726 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →