A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
Public ClinicalTrials.gov record NCT01794143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study
Study identification
- NCT ID
- NCT01794143
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- GRADE Study Group
- Other
- Enrollment
- 7,850 participants
Conditions and interventions
Interventions
- Sulfonylurea (glimepiride) Drug
- DPP-4 inhibitor (sitagliptin) Drug
- GLP-1 receptor agonist (liraglutide) Drug
- Insulin (glargine) Drug
Drug
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2013
- Primary completion
- Apr 29, 2021
- Completion
- Apr 29, 2021
- Last update posted
- Feb 9, 2026
2013 – 2021
United States locations
- U.S. sites
- 36
- U.S. states
- 25
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama-Birmingham | Birmingham | Alabama | — | — |
| Southwestern American Indian Center | Phoenix | Arizona | — | — |
| Veterans Medical Research Foundation, San Diego (San Diego VA) | San Diego | California | — | — |
| University of Colorado | Denver | Colorado | — | — |
| Yale University School of Medicine | New Haven | Connecticut | — | — |
| South Florida VA Foundation (Miami VA) | Miami | Florida | — | — |
| Atlanta VA Medical Center | Decatur | Georgia | — | — |
| Kaiser Permanente of Georgia | Duluth | Georgia | — | — |
| Pacific Health Research and Education Institute (VA Pacific Islands) | Honolulu | Hawaii | — | — |
| Indiana University School of Medicine | Indianapolis | Indiana | — | — |
| University of Iowa | Iowa City | Iowa | — | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | — | — |
| MedStar Health Research Institute | Hyattsville | Maryland | — | — |
| Massachusetts General Hospital | Boston | Massachusetts | — | — |
| University of Michigan | Ann Arbor | Michigan | — | — |
| International Diabetes Center | Minneapolis | Minnesota | — | — |
| University of Minnesota | Minneapolis | Minnesota | — | — |
| Washington University School of Medicine | St Louis | Missouri | — | — |
| University of Nebraska | Omaha | Nebraska | — | — |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | — | — |
| State University of New York (SUNY)-Downstate Medical Center | Brooklyn | New York | — | — |
| Columbia University Naomi Berrie Diabetes Center | New York | New York | — | — |
| Mount Sinai St. Luke's Hospital | New York | New York | — | — |
| Albert Einstein College of Medicine | The Bronx | New York | — | — |
| Duke University Medical Center | Durham | North Carolina | — | — |
| University of North Carolina Diabetes Care Center | Durham | North Carolina | — | — |
| University of Cincinnati | Cincinnati | Ohio | — | — |
| Case Western Reserve University School of Medicine | Cleveland | Ohio | — | — |
| Kaiser Permanente Northwest | Portland | Oregon | — | — |
| Oregon Health and Science University | Portland | Oregon | — | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | — | — |
| Baylor Endocrine Center | Dallas | Texas | — | — |
| University of Texas-Southwestern Medical Center | Dallas | Texas | — | — |
| Baylor College of Medicine | Houston | Texas | — | — |
| University of Texas Health Science Center | San Antonio | Texas | — | — |
| Seattle Institute for Biomedical and Clinical Research | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01794143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2026 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01794143 live on ClinicalTrials.gov.