Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia
Public ClinicalTrials.gov record NCT02739984. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Safety, Tolerability, and Efficacy of Evolocumab (AMG 145) on LDL-C in Subjects With Type 2 Diabetes Mellitus and Hypercholesterolemia/Mixed Dyslipidemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect of 12 weeks of subcutaneous evolocumab taken monthly compared with subcutaneous placebo taken monthly on low density lipoprotein cholesterol (LDL-C) in adults with type 2 diabetes mellitus and high blood cholesterol on a maximally tolerated oral dose of statin of at least moderate-intensity.
Study identification
- NCT ID
- NCT02739984
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 424 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 17, 2016 (Actual)
- Primary completion
- Aug 3, 2017 (Actual)
- Completion
- Aug 3, 2017 (Actual)
- Last update posted
- Aug 31, 2018
2016 – 2017
United States locations
- U.S. sites
- 46
- U.S. states
- 23
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Tuscumbia | Alabama | 35674 | — |
| Research Site | Phoenix | Arizona | 85012 | — |
| Research Site | Lomita | California | 90717 | — |
| Research Site | Los Angeles | California | 90057 | — |
| Research Site | Roseville | California | 95661 | — |
| Research Site | San Ramon | California | 94583 | — |
| Research Site | Spring Valley | California | 91978 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | Walnut Creek | California | 94598 | — |
| Research Site | Denver | Colorado | 80246 | — |
| Research Site | Lakewood | Colorado | 80227 | — |
| Research Site | Wilmington | Delaware | 19803 | — |
| Research Site | Boca Raton | Florida | 33434 | — |
| Research Site | Coral Gables | Florida | 33134 | — |
| Research Site | Daytona Beach | Florida | 32117 | — |
| Research Site | Fleming Island | Florida | 32003 | — |
| Research Site | Hollywood | Florida | 33021 | — |
| Research Site | Inverness | Florida | 34452 | — |
| Research Site | Jacksonville | Florida | 32216 | — |
| Research Site | Miami | Florida | 33135 | — |
| Research Site | Miami | Florida | 33136 | — |
| Research Site | West Palm Beach | Florida | 33401 | — |
| Research Site | Dunwoody | Georgia | 30338 | — |
| Research Site | Meridian | Idaho | 83642 | — |
| Research Site | Chicago | Illinois | 60611 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Chicago | Illinois | 60616 | — |
| Research Site | Louisville | Kentucky | 40213 | — |
| Research Site | Auburn | Maine | 04210 | — |
| Research Site | Scarborough | Maine | 04074 | — |
| Research Site | Salisbury | Maryland | 21804 | — |
| Research Site | Methuen | Massachusetts | 01844 | — |
| Research Site | Bay City | Michigan | 48706 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Las Vegas | Nevada | 89148 | — |
| Research Site | Albuquerque | New Mexico | 87106 | — |
| Research Site | New Windsor | New York | 12553 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Shelby | North Carolina | 28150 | — |
| Research Site | Tabor City | North Carolina | 28463 | — |
| Research Site | Columbus | Ohio | 43203 | — |
| Research Site | Norman | Oklahoma | 73069 | — |
| Research Site | Austin | Texas | 78749 | — |
| Research Site | Houston | Texas | 77070 | — |
| Research Site | Suffolk | Virginia | 23435 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02739984, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 31, 2018 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02739984 live on ClinicalTrials.gov.