CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)
Public ClinicalTrials.gov record NCT03504488. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Safety and Efficacy Dose Escalation / Dose Expansion Study of a CAB-ROR2-ADC, Alone and in Combination With a PD-1 Inhibitor, in Patients With Advanced Solid Tumors (Ph1) and Melanoma and NSCLC Patients (Ph2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Study identification
- NCT ID
- NCT03504488
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 132 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 27, 2018 (Actual)
- Primary completion
- Dec 30, 2024 (Actual)
- Completion
- Dec 30, 2024 (Actual)
- Last update posted
- Jan 15, 2025
2018 – 2024
United States locations
- U.S. sites
- 38
- U.S. states
- 18
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| City of Hope - Duarte | Duarte | California | 91010 | — |
| University of California, San Diego (UCSD) - Moores Cancer Center | La Jolla | California | 92093 | — |
| California Research Institute | Los Angeles | California | 90027 | — |
| USC Norris | Los Angeles | California | 90033 | — |
| UC Irvine Medical Center - Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California San Francisco | San Francisco | California | 94158 | — |
| American Institute of Research | Whittier | California | 90603 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Sarah Cannon Research Institute at Health One | Denver | Colorado | 80218 | — |
| Florida Cancer Specialists & Research Institute | Fleming Island | Florida | 32003 | — |
| Florida Cancer Specialists & Research Institute | Fort Myers | Florida | 33916 | — |
| Memorial Cancer Institute (MCI) | Hollywood | Florida | 33028 | — |
| Florida Cancer Specialist - North | St. Petersburg | Florida | 34474 | — |
| Memorial Sloan-Kettering Cancer Center | Tampa | Florida | 33612 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | — |
| Augusta University - Georgia Cancer Center | Augusta | Georgia | 30912 | — |
| Baptist Health Systems | Lexington | Kentucky | 40503 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute, Brownsboro Hospital Campus | Louisville | Kentucky | 40241 | — |
| Hematology/Oncology Clinic | Baton Rouge | Louisiana | 70809 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Comprehensive Cancer Care of Nevada | Las Vegas | Nevada | 89169 | — |
| OptumCare Cancer Care | Las Vegas | Nevada | 89169 | — |
| Roswell Park | Buffalo | New York | 14263 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| FirstHealth Outpatient Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| UPMC Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Medical University of South Carolina- Hollings Cancer Center | Charleston | South Carolina | 29407 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Mary Crowley Cancer Research | Dallas | Texas | 75230 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Utah - Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03504488, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 15, 2025 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03504488 live on ClinicalTrials.gov.