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Completed Phase 3 Interventional Results available

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

ClinicalTrials.gov ID: NCT04077437

Public ClinicalTrials.gov record NCT04077437. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 3:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Multi-Site Phase 3 Study of the Efficacy and Safety of Manualized MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder of Moderate or Greater Severity

Study identification

NCT ID
NCT04077437
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Resilient Pharmaceuticals
Industry
Enrollment
121 participants

Conditions and interventions

Interventions

  • Therapy Behavioral
  • Midomafetamine Drug
  • Placebo Drug

Behavioral · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 1, 2020
Primary completion
Oct 29, 2022
Completion
Nov 1, 2022
Last update posted
Jun 5, 2025

2020 – 2022

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
10
Facility City State ZIP Site status
New School Research Los Angeles California 90004
San Francisco Insight and Integration Center San Francisco California 94122
UCSF San Francisco California 94122
Aguazul Bluewater, Inc. Boulder Colorado 80304
Wholeness Center Fort Collins Colorado 80525
University of Connecticut Farmington Connecticut 06030
Ray Worthy Psychiatry LLC New Orleans Louisiana 70123
Trauma Research Foundation Boston Massachusetts 02446
New York University New York New York 10016
Nautilus Psychiatric Services New York New York 11012
Zen Therapeutic Solutions, LLC Mt. Pleasant South Carolina 29464
University of Wisconsin - Madison Madison Wisconsin 53705-2222

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04077437, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 5, 2025 · Synced Jun 26, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04077437 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →