ClinicalTrials.gov record

Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Attention to Emotion Study

ClinicalTrials.gov ID: NCT04105868

Public ClinicalTrials.gov record NCT04105868. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 5, 2026, 7:15 AM EDT

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Official title

Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Rates of depression increase rapidly during adolescence, especially for girls, and, thus, research is needed to spur the development of novel interventions to prevent adolescent depression. This project seeks to determine if a novel visuocortical probe of affect-biased attention (i.e., steady-state visual evoked potentials derived from EEG) can 1) be used to prospectively predict depression using a multi-wave repeated measures design and 2) modify affect-biased attention and buffer subsequent mood reactivity using real time neurofeedback. This work could ultimately lead to improved identification of adolescents who are at high risk for depression and directly inform the development of mechanistic treatment targets to be used in personalized intervention prescriptions for high-risk youth.

Study identification

NCT ID: NCT04105868
Recruitment status: Completed
Study type: Interventional
Phase: Not applicable
Lead sponsor: University of Pittsburgh; Other
Enrollment: 15 participants

Conditions and interventions

Conditions

Depression

Interventions

Neurofeedback Other

Other

Eligibility (public fields only)

Age range: 13 Years to 15 Years
Sex: Female
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 15, 2019
Primary completion: Sep 22, 2024
Completion: Mar 29, 2025
Last update posted: Nov 12, 2025

2019 – 2025

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
Western Psychiatric Institute and Clinic	Pittsburgh	Pennsylvania	15213	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04105868, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 12, 2025 · Synced Sep 5, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04105868 live on ClinicalTrials.gov.

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