An Efficacy and Safety Study of Ravulizumab in ALS Participants
Public ClinicalTrials.gov record NCT04248465. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel Group, Multicenter Study With an Open-Label Extension to Evaluate the Efficacy and Safety of Ravulizumab in Patients With Amyotrophic Lateral Sclerosis (ALS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.
Study identification
- NCT ID
- NCT04248465
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 382 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 30, 2020 (Actual)
- Primary completion
- Oct 17, 2021 (Actual)
- Completion
- Oct 17, 2021 (Actual)
- Last update posted
- Jan 10, 2023
2020 – 2021
United States locations
- U.S. sites
- 34
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Neuromuscular Research Center and Clinic | Phoenix | Arizona | 85028 | — |
| HonorHealth Research Institute | Scottsdale | Arizona | 85251 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California-Irvine | Orange | California | 92868 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| University of California San Diego Medical Center | San Diego | California | 92093-0949 | — |
| Norris MDA/ALS Center | San Francisco | California | 94115 | — |
| University of California San Francisco Medical Center | San Francisco | California | 94143 | — |
| University of Colorado Anschutz Medical Campus School of Medicine | Aurora | Colorado | 80045 | — |
| University of Florida at Shands Jacksonville | Jacksonville | Florida | 32209 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Indiana University Medical Center | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center Research Institute, Inc. | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Johns Hopkins University School Of Medicine | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Las Vegas Clinic | Las Vegas | Nevada | 89145 | — |
| Beth Israel Medical Center - PRIME | New York | New York | 10003 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| Atrium Health Neuroscience Institute | Charlotte | North Carolina | 28207 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| Allegheny Neurological Associates | Pittsburgh | Pennsylvania | 15212 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Austin Neuromuscular Center | Austin | Texas | 78756 | — |
| Houston Methodist Neurological Institute-Movement Disorders Clinic | Houston | Texas | 77030 | — |
| Nerve & Muscle Center of Texas | Houston | Texas | 77030 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Virginia Commonwealth University, Neurology Clinical and Translational Research Office | Richmond | Virginia | 23298 | — |
| Sentara Neurology Specialists | Virginia Beach | Virginia | 23456 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122-4470 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 61 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04248465, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 10, 2023 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04248465 live on ClinicalTrials.gov.