- Conditions
- ALS, Kennedy Disease, MND (Motor Neurone DIsease), PBP - Progressive Bulbar Palsy, PLS, PMA - Progressive Muscular Atrophy
- Interventions
- Not listed
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 5,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2030
- U.S. locations
- 14
- States / cities
- Loma Linda, California • Los Angeles, California • Gainesville, Florida + 10 more
Condition Directory
ALS clinical trials
Directory of U.S. ClinicalTrials.gov public records for ALS. Browse ALS recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official matching trials
39
Shown on this page
12
Local recruiting
11
Local phase groups
4
Showing 1–12 of 39 matching trials for ALS.
Indexed local directory records.
Phase distribution
Phase 1 8
Not applicable 7
Phase 2 6
Phase 3 1
Top locations
Top sponsors
Top therapies
Indexed official records
Open in full search- Conditions
- ALS, Amyotrophic Lateral Sclerosis
- Interventions
- Magnetic Resonance Imaging, Plasma neurofilament light chain (NfL) quantification
- Diagnostic Test
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 3
- States / cities
- Gainesville, Florida • Evanston, Illinois • Minneapolis, Minnesota
- Conditions
- ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Neurological Disorder
- Interventions
- Stentrode
- Device
- Lead sponsor
- Synchron, Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 5
- States / cities
- Jacksonville, Florida • Buffalo, New York • New York, New York + 2 more
- Conditions
- ALS, Multiple Sclerosis, Muscular Dystrophies, SCI - Spinal Cord Injury, Stroke
- Interventions
- PMT/Blackrock Combination Device
- Device
- Lead sponsor
- Karunesh Ganguly
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- ALS, Alzheimer's Disease, Dementia, Mild Cognitive Impairment, Parkinson's Disease
- Interventions
- 11C-MC1, 11C-PS13, 18f-florbetaben
- Drug
- Lead sponsor
- National Institute of Mental Health (NIMH)
- NIH
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 184 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2030
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- ALS
- Interventions
- Not listed
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 105 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ALS, Brainstem Stroke, Cervical Spinal Cord Injury, Spinal Cord Injuries, Tetraplegia
- Interventions
- BrainGate Neural Interface System
- Device
- Lead sponsor
- Leigh R. Hochberg, MD, PhD.
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- ALS, Alzheimer Disease, Cardiomyopathy Non-ischemic, Frontotemporal Dementia, Genetic Predisposition, Paraganglioma, Parkinson Disease, Pheochromocytoma, Polyneuropathies, Thoracic Aortic Aneurysm
- Interventions
- Behavioral nudge
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- ALS, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Cadasil, Cerebral Hemorrhage, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Chronic Traumatic Encephalopathy, Cognitive Impairment, Dementia, Diabetic Neuropathies, Frontotemporal Dementia, Lewy Body Disease, Lewy Body Variant of Alzheimer Disease, MSA - Multiple System Atrophy, Multi-System Degeneration, Nervous System Diseases, Neurodegenerative Diseases, Neurologic Disorders, Neurological Disorders, Neuropathy, Parkinson, Progressive Supranuclear Palsy, Stroke, Traumatic Brain Injury
- Interventions
- Intravenous and Intranasal BMSC
- Procedure
- Lead sponsor
- MD Stem Cells
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2027
- U.S. locations
- 2
- States / cities
- Westport, Connecticut • Coral Springs, Florida
- Conditions
- ALS, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Amyotrophic Lateral Sclerosis, Batten Disease, Cervical Cancer, Corticobasal Degeneration, Dementia, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Frontotemporal Dementia, Huntington Disease, INAD, Lewy Body Disease, Macular Degeneration, Multiple Sclerosis, Multiple System Atrophy, Ovarian Cancer, PTSD, Parkinson Disease, Parkinson's Disease and Parkinsonism, Post Traumatic Stress Disorder, Progressive Supranuclear Palsy, Uterine Cancer, Vaginal Cancer, Vulvar Cancer
- Interventions
- Biological Sample Collection
- Other
- Lead sponsor
- New York Stem Cell Foundation Research Institute
- Other
- Eligibility
- 30 Days and older
- Enrollment
- 10,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2045
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ALS, Age-Related Macular Degeneration, Allergies, Alopecia Areata, Alpha-Gal Syndrome, Alzheimer Disease, Amyloidosis, Ankylosing Spondylitis, Arthritis, Asthma, Atopic Dermatitis, Autism, Autoimmune Hepatitis, Behcet's Disease, Beta-Thalassemia, COPD, Cancer, Celiac Disease, Cirrhosis, Crohn Disease, Cystic Fibrosis, DMD, Diabetes, Dravet Syndrome, Fibromyalgia, Graves Disease, Heart Diseases, Hepatitis, Hidradenitis Suppurativa, ITP, Kidney Diseases, Leukemia, Lupus or SLE, Lymphoma, Multiple Sclerosis, Myasthenia Gravis, Parkinson Disease, Pemphigus Vulgaris, Psoriasis, Schizophrenia, Scleroderma, Sickle Cell Disease, Stroke, Thyroid Diseases, Ulcerative Colitis, Vasculitis, Vitiligo
- Interventions
- Specimen sample
- Diagnostic Test
- Lead sponsor
- Sanguine Biosciences
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Waltham, Massachusetts
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Lou Gehrig's Disease
- Interventions
- Not listed
- Lead sponsor
- Nova Southeastern University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 35 participants
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Fort Lauderdale, Florida
About this ALS clinical trials directory page
- What this page lists
- U.S. ClinicalTrials.gov public records that list ALS as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
- How to narrow results
- Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within ALS.
- Where the data comes from
- Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.
Related: all condition pages, browse by drug or therapy, browse by U.S. city, browse by sponsor, or open the full search for ALS.