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Active, not recruiting Phase 2 Interventional

Selective Avoidance of Nodal VolumEs at Minimal Risk (GCC 20110)

ClinicalTrials.gov ID: NCT04609280

Public ClinicalTrials.gov record NCT04609280. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 6:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single-arm, Single-stage Phase II Trial of Selective Avoidance of Nodal VolumEs at Minimal Risk (SAVER) in the Contralateral Neck of Patients With p16-positive Oropharynx Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase II, non-randomized, therapeutic trial with the primary objective to determine the efficacy of reduced contralateral (C/L) elective nodal treatment volumes in preventing C/L recurrences at 2 years in patients with p16 positive oropharyngeal squamous cell carcinoma undergoing definitive or adjuvant RT.

Study identification

NCT ID
NCT04609280
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
52 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2021
Primary completion
Nov 30, 2026
Completion
Nov 30, 2027
Last update posted
Aug 11, 2026

2021 – 2027

United States locations

U.S. sites
6
U.S. states
1
U.S. cities
4
Facility City State ZIP Site status
Maryland Proton Treatment Center Baltimore Maryland 21201
UMMC Baltimore Maryland 21201
University of Maryland Greenebaum Cancer Center Baltimore Maryland 21201
Upper Chesapeake Health Bel Air Maryland 21014
Central Maryland Radiation Oncology Columbia Maryland 21044
Baltimore Washington Medical Center Glen Burnie Maryland 21061

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04609280, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 11, 2026 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04609280 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →