Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)
Public ClinicalTrials.gov record NCT04730635. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Clinical Study to Evaluate a Cognitive Platform to Support Development of Symptomatic Therapies in Participants at Risk for Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to assess the ability of a repeated high-frequency site-based computerized cognitive assessment to evaluate the potential treatment effects of donepezil (MK-0000) compared with placebo among participants with mild cognitive impairment (MCI) or mild Alzheimer's Disease (AD). The primary study hypothesis is that the average percentage of correct responses on one card learning (OCL) task will be ≥2 percentage points in participants receiving donepezil compared with participants receiving placebo.
Study identification
- NCT ID
- NCT04730635
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2021
- Primary completion
- Jan 19, 2023
- Completion
- Feb 5, 2023
- Last update posted
- Oct 27, 2024
2021 – 2023
United States locations
- U.S. sites
- 8
- U.S. states
- 6
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Collaborative Neuroscience Network ( Site 0010) | Long Beach | California | 90806 | — |
| Velocity Clinical Research, Hallandale Beach ( Site 0013) | Hallandale | Florida | 33009 | — |
| Charter Research - Lady Lake ( Site 0025) | Lady Lake | Florida | 32159 | — |
| iResearch Atlanta ( Site 0005) | Decatur | Georgia | 30030 | — |
| iResearch Savannah ( Site 0023) | Savannah | Georgia | 31405 | — |
| Pennington Biomedical Research Center ( Site 0006) | Baton Rouge | Louisiana | 70808 | — |
| Insight Clinical Trials ( Site 0020) | Beachwood | Ohio | 44122 | — |
| North Texas Clinical Trials - Fort Worth - West Rosedale ( Site 0022) | Fort Worth | Texas | 76104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04730635, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 27, 2024 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04730635 live on ClinicalTrials.gov.