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Completed Phase 1 Interventional

A Study of PRT1419 in Patients With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT04837677

Public ClinicalTrials.gov record NCT04837677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:07 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-Label, Multicenter, Dose Escalation Study of PRT1419 in Patients With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 1 dose-escalation study of PRT1419, a myeloid cell leukemia 1 (MCL1) inhibitor, in patients with advanced solid tumors. The purpose of this study is to define the dosing schedule, maximally tolerated dose and/or estimate the optimal biological dose to be used in subsequent development of PRT1419.

Study identification

NCT ID
NCT04837677
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Prelude Therapeutics
Industry
Enrollment
26 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 10, 2021
Primary completion
Feb 5, 2023
Completion
Feb 5, 2023
Last update posted
Mar 14, 2023

2021 – 2023

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
7
Facility City State ZIP Site status
Sarah Cannon Research Institute at HealthONE Denver Colorado 80218
Florida Cancer Specialists Lake Mary Florida 32746
Florida Cancer Specialists Sarasota Florida 34232
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Thomas Jefferson University, Sidney Kimmel Cancer Center Philadelphia Pennsylvania 19107
UPMC Hillman Cancer Center Pittsburgh Pennsylvania 15232
Tennessee Oncology Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04837677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 14, 2023 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04837677 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →