Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)
Public ClinicalTrials.gov record NCT05231668. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b, Single Ascending Dose, Randomized, Double-blind Study to Evaluate the Safety, Tolerability, and Activity of SAR439459 in Adults With Osteogenesis Imperfecta
Study identification
- NCT ID
- NCT05231668
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 16 participants
Conditions and interventions
Conditions
Interventions
- SAR439459 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2022
- Primary completion
- Nov 11, 2024
- Completion
- Nov 11, 2024
- Last update posted
- Sep 10, 2025
2022 – 2024
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Health_Site Number: 8400006 | Los Angeles | California | 90095 | — |
| Yale University - Site Number:8400007 | New Haven | Connecticut | 06510 | — |
| Indiana University School of Medicine_Site Number: 8400002 | Indianapolis | Indiana | 46202 | — |
| Kennedy Krieger Institute_Site number 8400004 | Baltimore | Maryland | 21205 | — |
| Cincinnati Children's Hospital Medical Center Site Number : 8400010 | Cincinnati | Ohio | 45229 | — |
| Vanderbilt University Site Number : 8400011 | Nashville | Tennessee | 37232 | — |
| Baylor College of Medicine - Site Number:8400003 | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05231668, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05231668 live on ClinicalTrials.gov.