A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin
Public ClinicalTrials.gov record NCT05275400. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Parallel-Design, Open-Label Trial to Evaluate the Efficacy and Safety of LY3209590 Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin (QWINT-3)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The reason for this study is to see if the study drug insulin efsitora alfa (LY3209590) is safe and effective in participants with Type 2 diabetes that have already been treated with basal insulin. The study consists of a 3-week screening/lead-in period, a 78-week treatment period and a 5-week safety follow-up period. The study will last up to 86 weeks.
Study identification
- NCT ID
- NCT05275400
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 986 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 8, 2022 (Actual)
- Primary completion
- May 15, 2024 (Actual)
- Completion
- May 15, 2024 (Actual)
- Last update posted
- Jun 3, 2025
2022 – 2024
United States locations
- U.S. sites
- 38
- U.S. states
- 21
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Investigations | Little Rock | Arkansas | 72211 | — |
| John Muir Physician Network Research Center | Concord | California | 94520 | — |
| AMCR Institute | Escondido | California | 92025 | — |
| National Research Institute - Huntington Park | Huntington Park | California | 90255 | — |
| Scripps Whittier Diabetes Institute | La Jolla | California | 92037 | — |
| Diabetes Associates Medical Group | Orange | California | 92868 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Encore Medical Research | Hollywood | Florida | 33021 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| West Orange Endocrinology | Ocoee | Florida | 34761 | — |
| Balanced Life Health Care Solutions/SKYCRNG | Lawrenceville | Georgia | 30046 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50265 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| HealthPartners Institute dba International Diabetes Center | Minneapolis | Minnesota | 55416 | — |
| SKY Clinical Research Network Group - Hall | Fayette | Mississippi | 39069 | — |
| Clinvest Research LLC | Springfield | Missouri | 65807 | — |
| Palm Research Center Tenaya | Las Vegas | Nevada | 89128 | — |
| Albany Medical College, Division of Community Endocrinology | Albany | New York | 12203 | — |
| NYC Research | New York | New York | 10016 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| Aventiv Research Inc | Columbus | Ohio | 43213 | — |
| Intend Research, LLC | Norman | Oklahoma | 73069 | — |
| Heritage Valley Medical Group, Inc. | Beaver | Pennsylvania | 15009 | — |
| Jefferson Clinical Research Institute (JCRI) | Philadelphia | Pennsylvania | 19114 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| Gadolin Research | Beaumont | Texas | 77702 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| Juno Research | Houston | Texas | 77040 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Texas Diabetes & Endocrinology, P.A. | Round Rock | Texas | 78681 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Rainier Clinical Research Center | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 89 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05275400, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2025 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05275400 live on ClinicalTrials.gov.