A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time
Public ClinicalTrials.gov record NCT05362058. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Parallel-Design, Open-Label, Randomized Control Study to Evaluate the Efficacy and Safety of LY3209590 as a Weekly Basal Insulin Compared to Insulin Degludec in Insulin Naïve Adults With Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the effect and safety of insulin efsitora alfa (LY3209590) compared to degludec in adult participants with type 2 diabetes who are starting basal insulin for the first time. The study consists of a 1-week screening period, a 2-week lead-in period, a 52-week treatment period, and a 5-week safety follow-up period. The study will last up to 60 weeks.
Study identification
- NCT ID
- NCT05362058
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 928 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2, 2022
- Primary completion
- Apr 9, 2024
- Completion
- Apr 9, 2024
- Last update posted
- May 15, 2025
2022 – 2024
United States locations
- U.S. sites
- 30
- U.S. states
- 19
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neighborhood Healthcare Institute of Health | Escondido | California | 92025 | — |
| Valley Research | Fresno | California | 93720 | — |
| NorCal Medical Research, Inc | Greenbrae | California | 94904 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Southern California Dermatology, Inc. | Santa Ana | California | 92701 | — |
| New West Physicians Clinical Research | Golden | Colorado | 80401 | — |
| New England Research Associates, LLC | Bridgeport | Connecticut | 06606 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32204 | — |
| East Coast Institute for Research - Canton | Canton | Georgia | 30114 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Central Illinois Diabetes and Clinical Research a Division of Prairie Education and Research Cooperative | Springfield | Illinois | 62711 | — |
| Qualmedica Research, LLC | Evansville | Indiana | 47715 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50265 | — |
| Qualmedica Research | Bowling Green | Kentucky | 42101 | — |
| MedStar Health Research Institute (MedStar Physician Based Research Network) | Hyattsville | Maryland | 20782 | — |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | — |
| SKY Clinical Research Network Group-Quinn | Ridgeland | Mississippi | 39157 | — |
| Clinvest Research LLC | Springfield | Missouri | 65807 | — |
| Clarity Clinical Research | East Syracuse | New York | 13057 | — |
| Great Lakes Medical Research, LLC | Westfield | New York | 14787 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Lucas Research, Inc | Morehead City | North Carolina | 28557 | — |
| Intend Research, LLC | Norman | Oklahoma | 73069 | — |
| Jefferson Clinical Research Institute (JCRI) | Philadelphia | Pennsylvania | 19114 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| Juno Research | Houston | Texas | 77040 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| North Hills Family Medicine/North Hills Medical Research | North Richland Hills | Texas | 76180 | — |
| Multicare Institute for Research and Innovation | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05362058, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2025 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05362058 live on ClinicalTrials.gov.