Phase 2b Study of ALTO-100 in MDD
Public ClinicalTrials.gov record NCT05712187. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of ALTO-100 With an Open-Label Extension in Adults With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine efficacy differences between ALTO-100 and placebo, used either as monotherapy or adjunctively to an antidepressant, related to patient characteristics.
Study identification
- NCT ID
- NCT05712187
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 301 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 10, 2023 (Actual)
- Primary completion
- Sep 5, 2024 (Actual)
- Completion
- Oct 24, 2024 (Actual)
- Last update posted
- Sep 8, 2025
2023 – 2024
United States locations
- U.S. sites
- 34
- U.S. states
- 18
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 174 | Birmingham | Alabama | 35294 | — |
| Site 173 | Huntsville | Alabama | 35801 | — |
| Site 136 | Chandler | Arizona | 85226 | — |
| Site 139 | Little Rock | Arkansas | 72211 | — |
| Site 141 | Costa Mesa | California | 92626 | — |
| Site 118 | Fresno | California | 93703 | — |
| Site 181 | Imperial | California | 92251 | — |
| Site 182 | Oceanside | California | 92056 | — |
| Site 188 | Oceanside | California | 92056 | — |
| Site 179 | Rancho Cucamonga | California | 91730 | — |
| Site 116 | Sacramento | California | 95655 | — |
| Site 185 | Centennial | Colorado | 80112 | — |
| Site 186 | Brooksville | Florida | 34613 | — |
| Site 204 | Jacksonville | Florida | 32256 | — |
| Site 205 | Orlando | Florida | 32801 | — |
| Site 212 | Tampa | Florida | 33629 | — |
| Site 213 | Tampa | Florida | 33629 | — |
| Site 137 | Carmel | Indiana | 46032 | — |
| Site 151 | Baltimore | Maryland | 21229 | — |
| Site 108 | Jackson | Mississippi | 39216 | — |
| Site 171 | Jackson | Mississippi | 39216 | — |
| Site 142 | Lincoln | Nebraska | 68562 | — |
| Site 144 | Las Vegas | Nevada | 89102 | — |
| Site 178 | Albuquerque | New Mexico | 87109 | — |
| Site 184 | Brooklyn | New York | 11229 | — |
| Site 180 | New York | New York | 10022 | — |
| Site 210 | New York | New York | 10128 | — |
| Site 175 | Westlake | Ohio | 44145 | — |
| Site 157 | North Charleston | South Carolina | 29405 | — |
| Site 183 | Memphis | Tennessee | 38119 | — |
| Site 147 | Fort Worth | Texas | 76104 | — |
| Site 120 | Houston | Texas | 77054 | — |
| Site 172 | Houston | Texas | 77081 | — |
| Site 121 | Draper | Utah | 84020 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05712187, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 8, 2025 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05712187 live on ClinicalTrials.gov.