Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:00 PM EDT

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Showing 1–4 of 4 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional

Pilot Decentralized Trial

NCT05419869
Conditions
Major Depressive Disorder
Interventions
ALTO-100 PO Tablet
Drug
Lead sponsor
Alto Neuroscience
Industry
Eligibility
18 Years to 64 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Coral Gables, Florida • Jackson, Mississippi
Conditions
Major Depressive Disorder
Interventions
ALTO-100, Placebo
Drug
Lead sponsor
Alto Neuroscience
Industry
Eligibility
18 Years to 64 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
34
States / cities
Birmingham, Alabama • Huntsville, Alabama • Chandler, Arizona + 26 more
Completed Phase 2 Interventional

ALTO-100 in MDD and/or PTSD

NCT05117632
Conditions
Major Depressive Disorder, Post Traumatic Stress Disorder
Interventions
ALTO-100 PO tablet
Drug
Lead sponsor
Alto Neuroscience
Industry
Eligibility
18 Years to 69 Years
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
23
States / cities
Tempe, Arizona • Little Rock, Arkansas • Costa Mesa, California + 18 more
Conditions
Bipolar Disorder I or II With a Major Depressive Episode
Interventions
ALTO-100, Placebo
Drug
Lead sponsor
Alto Neuroscience
Industry
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
27
States / cities
Chandler, Arizona • Phoenix, Arizona • Yuma, Arizona + 22 more