A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes
Public ClinicalTrials.gov record NCT05872620. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Once-Daily Oral LY3502970 Compared With Placebo in Adult Participants With Obesity or Overweight and Type 2 Diabetes (ATTAIN-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will investigate the safety and efficacy of once daily oral treatment with orforglipron compared with placebo on body weight in adult participants with obesity or overweight and type 2 diabetes. The study will last about 77 weeks and may include up to 22 visits.
Study identification
- NCT ID
- NCT05872620
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,613 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2023
- Primary completion
- Aug 7, 2025
- Completion
- Aug 7, 2025
- Last update posted
- Sep 3, 2026
2023 – 2025
United States locations
- U.S. sites
- 37
- U.S. states
- 20
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research - Pelham | Pelham | Alabama | 35124 | — |
| Novak Clinical Research - Tucson - North La Cholla Boulevard | Tucson | Arizona | 85741 | — |
| Yuma Clinical Trials | Yuma | Arizona | 85364 | — |
| AMCR Institute | Escondido | California | 92025 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Velocity Clinical Research, Westlake | Los Angeles | California | 90057 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32216 | — |
| South Florida Clinical Research Institute | Margate | Florida | 33063 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Balanced Life Health Care Solutions/SKYCRNG | Lawrenceville | Georgia | 30046 | — |
| Endocrine Research Solutions, Inc. | Roswell | Georgia | 30076 | — |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | — |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96813 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50265 | — |
| MedStar Good Samaritan Hospital | Baltimore | Maryland | 21239 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| IMA Clinical Research | Albuquerque | New Mexico | 87109 | — |
| Albany Medical College, Division of Community Endocrinology | Albany | New York | 12203 | — |
| Albany Stratton VA Medical Center | Albany | New York | 12208 | — |
| NYC Research INC | Long Island City | New York | 11106 | — |
| Accellacare - Raleigh | Raleigh | North Carolina | 27609 | — |
| Summit Headlands | Portland | Oregon | 97210 | — |
| Alliance for Multispecialty Research, LLC | Knoxville | Tennessee | 37909 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| Soma Clinical Trials | Denison | Texas | 75020 | — |
| Epic Medical Research - DeSoto | DeSoto | Texas | 75115 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Diabetes and Glandular Disease Center | San Antonio | Texas | 78229 | — |
| VIP Trials | San Antonio | Texas | 78230 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Universal Research Group | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05872620, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05872620 live on ClinicalTrials.gov.