A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone
Public ClinicalTrials.gov record NCT05971940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Once Daily Oral LY3502970 Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to determine safety and efficacy of orforglipron compared with placebo in adult participants with type 2 diabetes and inadequate glycemic control with diet and exercise alone. The study will last approximately 54 weeks.
Study identification
- NCT ID
- NCT05971940
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 559 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 9, 2023 (Actual)
- Primary completion
- Apr 3, 2025 (Actual)
- Completion
- Apr 3, 2025 (Actual)
- Last update posted
- Sep 3, 2026
2023 – 2025
United States locations
- U.S. sites
- 41
- U.S. states
- 22
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Syed Research Consultants Llc | Sheffield | Alabama | 35660 | — |
| Epic Medical Research - Surprise | Surprise | Arizona | 85378 | — |
| Quality of Life Medical & Research Center | Tucson | Arizona | 85712 | — |
| Neighborhood Healthcare Institute of Health | Escondido | California | 92025 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Ark Clinical Research | Long Beach | California | 90815 | — |
| Velocity Clinical Research, Westlake | Los Angeles | California | 90057 | — |
| Infinity Clinical Research - Norco | Norco | California | 92860 | — |
| Norcal Endocrinology & Internal Medicine | San Ramon | California | 94583 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Connecticut Clinical Research - Cromwell | Cromwell | Connecticut | 06416 | — |
| Invictus Clinical Research Group | Coconut Creek | Florida | 33073 | — |
| Hillcrest Medical Research | DeLand | Florida | 32720 | — |
| K2 Medical Research | Maitland | Florida | 32751 | — |
| Global Health Research Center, Inc. | Miami Lakes | Florida | 33016 | — |
| West Orange Endocrinology | Ocoee | Florida | 34761 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Family First Medical Center | Idaho Falls | Idaho | 83404 | — |
| American Health Network of Indiana, LLC - Muncie | Muncie | Indiana | 47304 | — |
| Tekton Research - Wichita | Wichita | Kansas | 67218 | — |
| Alliance for Multispecialty Research, LLC | New Orleans | Louisiana | 70119 | — |
| Revival Research Institute | Dearborn | Michigan | 48126 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| Ellipsis Research Group - Brooklyn - 7th Street | Brooklyn | New York | 11215 | — |
| Central New York Clinical Research | Manlius | New York | 13104 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Lucas Research - New Bern | New Bern | North Carolina | 28562 | — |
| Centricity Research Dublin Multispecialty | Dublin | Ohio | 43016 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| The Corvallis Clinic, P.C. | Corvallis | Oregon | 97330 | — |
| Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair | Pittsburgh | Pennsylvania | 15243 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| The Research Center of The Upstate | Greenville | South Carolina | 29607 | — |
| MDFirst Research, LLC | Lancaster | South Carolina | 29720 | — |
| The Jackson Clinic | Jackson | Tennessee | 38305 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| Juno Research | Houston | Texas | 77040 | — |
| Endocrine Ips, Pllc | Houston | Texas | 77079 | — |
| Amir A Hassan, MD, PA | Houston | Texas | 77089 | — |
| Burke Internal Medicine and Research | Burke | Virginia | 22015 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05971940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05971940 live on ClinicalTrials.gov.