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Active, not recruiting Phase 3 Interventional

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

ClinicalTrials.gov ID: NCT06297603

Public ClinicalTrials.gov record NCT06297603. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Multicenter, Double-Blind Study to Investigate the Efficacy and Safety of Retatrutide Once Weekly Compared With Placebo in Adult Participants With Type 2 Diabetes, Moderate or Severe Renal Impairment With Inadequate Glycemic Control on Basal Insulin With or Without Metformin and/or SGLT2 Inhibitor

Study identification

NCT ID
NCT06297603
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
320 participants

Conditions and interventions

Interventions

  • Retatrutide Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 14, 2024
Primary completion
Sep 30, 2026
Completion
Oct 31, 2026
Last update posted
Jul 19, 2026

2024 – 2026

United States locations

U.S. sites
28
U.S. states
16
U.S. cities
27
Facility City State ZIP Site status
Nephrology Consultants Huntsville Alabama 35805
Clinical Research Institute of Arizona (CRI) - Sun City West Sun City West Arizona 85375
Kidney & Hypertension Center - Apple Valley Apple Valley California 92307
Hope Clinical Research, Inc. Canoga Park California 91303
Neighborhood Healthcare Institute of Health Escondido California 92025
EndoTrials Center for Clinical Research La Mesa California 91942
UCLA South Bay Endocrinology Torrance California 90505
Northeast Research Institute (NERI) Fleming Island Florida 32003
Encore Medical Research - Weston Weston Florida 33331
Orita Clinical Research Decatur Georgia 30034
CARE Institute Idaho Falls Idaho 83404
Cotton O'Neil Diabetes & Endocrinology Topeka Kansas 66606
Billings Clinic Billings Montana 59101
Excel Clinical Research, LLC Las Vegas Nevada 89109
Albany Medical College, Division of Community Endocrinology Albany New York 12203
NYC Research INC Long Island City New York 11106
Research Foundation of SUNY - University of Buffalo Williamsville New York 14221
University of North Carolina Medical Center Chapel Hill North Carolina 27514
Central States Research Tulsa Oklahoma 74136
Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair Pittsburgh Pennsylvania 15243
AM Diabetes & Endocrinology Center Bartlett Tennessee 38133
Velocity Clinical Research, Dallas Dallas Texas 75230
Prime Revival Research Institute, LLC Flower Mound Texas 75098
Juno Research Houston Texas 77040
PlanIt Research, PLLC Houston Texas 77079
Southern Endocrinology Associates Mesquite Texas 75149
Texas Valley Clinical Research Weslaco Texas 78596
Diabetes & Endocrine Treatment Specialists Sandy City Utah 84093

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06297603, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 19, 2026 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06297603 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →